Effects of virtual reality in the augmentation of neuronal network plasticity (C07)

虚拟现实对增强神经网络可塑性的影响（C07）

• 批准号: 280151463
• 金额: --
• 依托单位: Klinik und Poliklinik für Psychiatrie und Psychotherapie
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2015
• 资助国家: 德国
• 起止时间: 2014-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/280151463?language=en
• 关键词: Effects; virtual; reality; augmentation; neuronal

A main finding of the previous funding period was that brain-plasticity effects in the hippocampal-prefrontal network in response to a video game intervention are primarily induced by demanding spatial navigation (training of a 3D versus 2D version of the same video game). Clinical data of schizophrenia patients show a significant decrease in general psychopathology in the 3D training condition. Based on this encouraging evidence our goal for the next funding period is to (1) maximize the plasticity effects by using virtual-reality technology in the game, (2) unravel the time course and sequence of network plasticity effects and (3) to search for predictors of long-term plasticity in functional connectivity measures prior to training.

在之前的研究中，一个主要的发现是，海马体-前额叶网络对电子游戏干预的大脑可塑性效应主要是由要求空间导航（同样的电子游戏的3D和2D版本的训练）引起的。精神分裂症患者的临床资料显示，在3D训练条件下，一般精神病理学显著下降。基于这一令人鼓舞的证据，我们下一个资助期的目标是：(1)通过在游戏中使用虚拟现实技术来最大化可塑性效应，(2)揭示网络可塑性效应的时间过程和顺序，(3)在训练前的功能连接测量中寻找长期可塑性的预测因素。