Bodipy-tagged ligands for transition metal complexes

过渡金属配合物的 Bodipy 标记配体

• 批准号: 280718014
• 负责人: Professor Dr. Herbert Plenio
• 金额: --
• 依托单位: Fachgebiet Anorganische Chemie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2015
• 资助国家: 德国
• 起止时间: 2014-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/280718014?language=en
• 关键词: Bodipy; tagged; ligands; transition; metal

The overall target of this project is to utilize fluorescence-based methods, which are well established in biochemistry and molecular biology, for new applications in organometallic chemistry and in homogeneous catalysis aiming for the elucidation of mechanistic steps. This requires the synthesis of Bodipy-fluorophore tagged organometallic complexes. The fluorescence light emitted from the respective excited complexes should provide information on the metal complexes and on characteristic changes in the coordination sphere following chemical reactions.Three sub-projects are envisaged: a) fluorogenic reactions of Crabtree-type catalysts with hydrogen; b) the observation of the formation of dinuclear metal complexes tagged with complementary fluorophores following decomposition or deactivation reactions of the active species during homogeneous catalysis; c) the observation of ion pairing of cationic organometallic complexes and the respective anions by again using complementary fluorophore tagged ions. Complementary means that two different fluorophores are utilized, which form a FRET-pair upon close spatial association. Consequently, a FRET-signal is only observed when this condition is met and this FRET-signal then provides direct information on pair-formation reactions.

这个项目的总体目标是利用生物化学和分子生物学中成熟的基于荧光的方法，在有机金属化学和均相催化中的新应用，旨在阐明机理步骤。这就需要合成BODIPY-荧光团标记的金属有机配合物。从各自激发的络合物发出的荧光应该提供关于金属络合物的信息和化学反应后配位球中的特征变化的信息。设想了三个分项目：a)Crabtree型催化剂与氢的荧光反应；b)观察在均相催化过程中活性物种的分解或失活反应后，标记了互补荧光团的双核金属络合物的形成；c)再次使用标记的互补荧光团观察阳离子有机金属络合物和相应阴离子的离子配对。互补意味着利用两个不同的荧光团，这两个荧光团在紧密的空间关联时形成FRET对。因此，只有当满足这一条件时，才能观察到FRET信号，然后该FRET信号提供关于配对形成反应的直接信息。

项目成果

Switched fluorescence and photosensitization based on reversible ion-pairing.

基于可逆离子配对的开关荧光和光敏化

• DOI: 10.1039/d2cc05195h
• 发表时间: 2022
• 期刊: Chemical communications
• 影响因子: 4.9
• 作者: S. Popov;H. Plenio
• 通讯作者: H. Plenio