Oxidative stress, related blood cell DNA methylation and the development of cancer

氧化应激、相关血细胞 DNA 甲基化和癌症的发展

• 批准号: 286016687
• 负责人: Privatdozent Dr. Ben Schöttker
• 金额: --
• 依托单位: Centre for Prevention and Health Services Research (PZO) (aufgelöst)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2015
• 资助国家: 德国
• 起止时间: 2014-12-31 至 2018-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/286016687?language=en
• 关键词: Oxidative; stress; related; blood; cell

The overall objective of the project is to evaluate the association of oxidative stress serum markers and oxidative stress related blood cell DNA methylation at the nucleoredoxin gene with cancer development and to identify potential preventive factors for adverse oxidative stress effects.

该项目的总体目标是评估氧化应激血清标志物和氧化应激相关的血细胞核氧还蛋白基因DNA甲基化与癌症发展的关系，并确定不利氧化应激影响的潜在预防因素。

项目成果

Association of Serum Markers of Oxidative Stress With Incident Major Cardiovascular Events, Cancer Incidence, and All-Cause Mortality in Type 2 Diabetes Patients: Pooled Results From Two Cohort Studies

• DOI: 10.2337/dc19-0292
• 发表时间: 2019-06
• 期刊: Diabetes Care
• 影响因子: 16.2
• 作者: Y. Xuan;Xīn Gào;Ankita Anusruti;B. Holleczek;E. Jansen;D. C. Muhlack;H. Brenner;B. Schöttker

The associations of DNA methylation alterations in oxidative stress-related genes with cancer incidence and mortality outcomes: a population-based cohort study

• DOI: 10.1186/s13148-018-0604-y
• 发表时间: 2019-01-24
• 期刊: CLINICAL EPIGENETICS
• 影响因子: 5.7
• 作者: Gao, Xin;Zhang, Yan;Schoettker, Ben
• 通讯作者: Schoettker, Ben

Factors associated with high oxidative stress in patients with type 2 diabetes: a meta-analysis of two cohort studies

• DOI: 10.1136/bmjdrc-2019-000933
• 发表时间: 2020-01-01
• 期刊: BMJ OPEN DIABETES RESEARCH & CARE
• 影响因子: 4.1
• 作者: Anusruti, Ankita;Xuan, Yang;Schottker, Ben
• 通讯作者: Schottker, Ben

Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study

• DOI: 10.1159/000504711
• 发表时间: 2020-02-01
• 期刊: OBESITY FACTS
• 影响因子: 3.6
• 作者: Anusruti, Ankita;Jansen, Eugene H. J. M.;Schoettker, Ben
• 通讯作者: Schoettker, Ben