Real-time precision functional network mapping of the human brain for neurosurgical applications

对于2022财年，我们又扫描了10名健康志愿者，完成了所有20名健康对照的MRI扫描。所有参与者都接受了两次成像治疗，间隔约一个月。所获取的MRI数据包括结构T1 MRI数据、一小时静息状态功能MRI数据和扩散加权MRI数据。此外，我们还获得了特发性震颤患者的MRI数据。对从健康对照组获得的数据集的初步分析表明，随着分析中纳入更多的体积，全脑FCOR图的可靠性最初显示出快速增长。随着体积的增加，可靠性测量后来停滞不前，这表明可靠性有一个上限，以及达到这个上限的最佳体积数量。我们还开始了对特发性震颤患者数据的分析。这项工作将于2023财年完成。

For the FY2022, we have scanned 10 more healthy volunteers, completing the MRI scans of all 20 healthy controls. All participants underwent two imaging sessions, about one month apart. Acquired MRI data includes structural T1 MRI data, an hour of resting state functional MRI data, and diffusion-weighted MRI data. Additionally, we have also acquired the MRI data from patients with essential tremor. Preliminary analysis of the acquired datasets from healthy controls have shown that the reliability of the whole-brain FCOR map exhibited an initial rapid increase as more volumes are incorporated into the analysis. With more volumes added, the reliability measure later plateaus suggesting an upper limit to the reliability as well as an optimal number of volumes to achieve this limit. We have also started the analysis of the data from patients with essential tremor. This will be completed in FY2023.