Exercise, diet and brain training-based cocktail intervention for improving physical and cognitive functions in the elderly

基于运动、饮食和大脑训练的鸡尾酒干预可改善老年人的身体和认知功能

• 批准号: 21K10397
• 负责人: Hossain Mahbub
• 金额: $ 2.75万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2021
• 资助国家: 日本
• 起止时间: 2021-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21K10397/
• 关键词: Exercise; Diet; Brain training; Plasma free amino acids; Gut microbiota; gut microbiota

We have completed data collection at baseline, and at 6th and 12th months of intervention in three groups of elderly (aged between 75 to 83 years) volunteers: 1) Exercise Intervention Group (40 people); 2) Yogurt Ingestion Group (20 people); and 3) Control Group (40 people). Also, we have completed the statistical analysis of relevant data on demographic and clinical variables collected at baseline and after 6th months of intervention.Now we are performing the analysis of the relevant data on cognitive function and balance tests. Furthermore, the quantitative measurements of plasma free amino acid concentrations (PFAA) in blood samples collected at baseline and after 6th month of intervention, and baseline gut microbiota have been completed.

我们已经完成了基线和干预6个月和12个月时三组老年志愿者(年龄在75岁到83岁之间)的数据收集：1)运动干预组(40人)；2)酸奶组(20人)；3)对照组(40人)。此外，我们已经完成了在基线和干预6个月后收集的人口统计学和临床变量的相关数据的统计分析。现在，我们正在对认知功能和平衡测试的相关数据进行分析。此外，在基线和干预6个月后采集的血样和基线肠道微生物区系中的血浆游离氨基酸浓度(PFAA)的定量测量已经完成。