The neural and glial bases of diet-induced deficits in control of reward-seeking actions

饮食引起的奖励寻求行为控制缺陷的神经和神经胶质基础

• 批准号: 490692
• 负责人: Corbit Laura
• 金额: $ 63.81万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-09-01 至 2028-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=490692&lang=en
• 关键词: Diet-Induced Obesity; Dorsal Striatum; Goal-Directed Learning; Habit Learning; Instrumental Learning

Attempts to lose weight typically fail over the long term despite strong motivation and determined efforts. We recently found that excess sugar and fat in the diet promotes reliance on habits at the expense of more flexible decision-making based on the va

尽管有强烈的动机和坚定的努力，但长期减肥的尝试通常会失败。我们最近发现，饮食中过量的糖和脂肪会促进对习惯的依赖，而牺牲了基于VA的更灵活的决策。