The interaction between High Fat Diet, lung stem cells, and lung fibrosis

高脂肪饮食、肺干细胞和肺纤维化之间的相互作用

• 批准号: 20K08548
• 负责人: Hegab Ahmed E
• 金额: $ 2.75万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K08548/
• 关键词: lung stem cells; lung fibrosis; high fat diet; High fat diet; Fatty acids; Fibrosis; bronchioalveolar cells; Alveolar type-2 cells; fatty a. oxidation; fibrosis; alveolar type-2 cells; Calorie restriction

项目成果

Effect of High Fat Diet on the Severity and Repair of Lung Fibrosis in Mice

• DOI: 10.1089/scd.2021.0050
• 发表时间: 2021-08-24
• 期刊: STEM CELLS AND DEVELOPMENT
• 影响因子: 4
• 作者: Hegab, Ahmed E.;Ozaki, Mari;Fukunaga, Koichi
• 通讯作者: Fukunaga, Koichi

Enhanced fatty-acid oxidation slows the contribution of AT2 stem cells in the lung repair process after a fibrosis-inducing injury

增强的脂肪酸氧化减缓了 AT2 干细胞在纤维化诱导损伤后肺修复过程中的贡献

• 发表时间: 2022
• 作者: MASUDA TAKESHI;WAKABAYASHI YU;NAKASHIMA TAKU;NISHIMURA YOSHIFUMI;SHIMOJI KIYOFUMI;YAMAGUCHI KAKUHIRO;SAKAMOTO SHINJIRO;HORIMASU YASUSHI;MIYAMOTO SHINTARO;SENOO TADASHI;IWAMOTO HIROSHI;OHSHIMO SHINICHIRO;FUJITAKA KAZUNORI;HAMADA HIRONOBU;HATTORI NOBORU;Ahmed E Hegab
• 通讯作者: Ahmed E Hegab