The development of novel strategies for the prevention and treatment of recalcitrant bone fractures and osteoporosis through the utilization of ultrafine bubbles

利用超细气泡开发预防和治疗顽固性骨折和骨质疏松症的新策略

• 批准号: 20K09460
• 负责人: Ebina Kosuke
• 金额: $ 2.75万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K09460/
• 关键词: 廃用性骨粗鬆症; 難治性骨折; 酸素; ウルトラファインバブル; 骨癒合; 治療

项目成果

関節リウマチ伴う骨関節破壊機序とその対策-RANKL制御の意義-

类风湿关节炎相关骨关节破坏机制及对策 - RANKL控制的意义 -

• 发表时间: 2022
• 作者: 蛯名耕介;平尾眞;惠谷悠紀;前田悠一;沖田康孝;熊ノ郷淳;岡田誠司
• 通讯作者: 岡田誠司

Combined effect of teriparatide and an anti-RANKL monoclonal antibody on bone defect regeneration in mice with glucocorticoid-induced osteoporosis

• DOI: 10.1016/j.bone.2020.115525
• 发表时间: 2020-10-01
• 期刊: BONE
• 影响因子: 4.1
• 作者: Etani, Yuki;Ebina, Kosuke;Yoshikawa, Hideki
• 通讯作者: Yoshikawa, Hideki

Effects of prior osteoporosis treatment on 12-month treatment response of romosozumab in patients with postmenopausal osteoporosis

• DOI: 10.1016/j.jbspin.2021.105219
• 发表时间: 2021-06-05
• 期刊: JOINT BONE SPINE
• 影响因子: 4.2
• 作者: Ebina, Kosuke;Tsuboi, Hideki;Okada, Seiji
• 通讯作者: Okada, Seiji

Favorable clinical response and drug retention of anti-IL-6 receptor inhibitor in rheumatoid arthritis with high CRP levels: the ANSWER cohort study

• DOI: 10.1080/03009742.2021.1947005
• 发表时间: 2021-09-06
• 期刊: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
• 影响因子: 2.1
• 作者: Nakayama, Y.;Hashimoto, M.;Morinobu, A.
• 通讯作者: Morinobu, A.

Impact of the duration of previous osteoporosis treatment on the effect of romosozumab in patients with postmenopausal osteoporosis

绝经后骨质疏松症患者既往骨质疏松症治疗时间对罗莫佐单抗疗效的影响

• DOI: 10.1007/s00198-022-06545-1
• 发表时间: 2022
• 期刊: Osteoporosis International
• 影响因子: 4
• 作者: Ebina Kosuke;Etani Yuki;Tsuboi Hideki;Nagayama Yoshio;Kashii Masafumi;Miyama Akira;Kunugiza Yasuo;Hirao Makoto;Okamura Gensuke;Noguchi Takaaki;Takami Kenji;Goshima Atsushi;Miura Taihei;Fukuda Yuji;Kurihara Takuya;Okada Seiji;Nakata Ken
• 通讯作者: Nakata Ken