On searching antimicrobial agents among natural products:Fighting against Superbug

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Antimicrobial agents are drugs that can kill microorganisms or stop their growth. massive imprudent usage of antibiotics in clinical practice for both human and livestock has resulted in resistance of bacteria to antimicrobial agents. Our research focused on finding natural antibiotic compounds based on traditional medicine formulas. We applied various machine learning algorithms such as Lasso regression, Random Forest and XGBoost, deep learning to Jamu and TCM formulas aiming to finding natural antibiotic plants and compounds. Based on our research in the current fiscal year, we published two papers in journals with reasonable impact factors. One of the papers published in the journal Antibiotics (Impact Factor 4.94) identified antibiotic plants based on Jamu formulas. Another paper published in the journal Methods (Impact Factor 4.647) found out antibacterial natural compounds based on TCM formulas. We also published two papers in IEEE conferences.