Masticatory muscles thickness and its association with signs and symptoms of temporomandibular disorders

咀嚼肌厚度及其与颞下颌疾病体征和症状的关系

• 批准号: 314839918
• 负责人: Dr. Amro Daboul, Ph.D.
• 金额: --
• 依托单位: Poliklinik für Zahnärztliche Prothetik, Alterszahnheilkunde und medizinische Werkstoffkunde
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2016
• 资助国家: 德国
• 起止时间: 2015-12-31 至 2017-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/314839918?language=en
• 关键词: Masticatory; muscles; thickness; its; association

Masticatory function and bite force are known to be impaired in many patients with temporomandibular disorders (TMD), but the susceptibility of their masticatory muscles to fatigue and atrophy because of missing teeth or oral para-functional activity is less certain.In this proposed study, the effects of occlusal support on the masticatory muscles and subsequently on the temporomandibular joint will be studied.The effects of different occlusal support that are present in patients with signs and symptoms of TMD on the cross- sectional area of three jaw muscles; the masseter, medial pterygoid and lateral pterygoid will be investigated using MRI. Magnetic resonance images of the head for 2440 subjects aged between 20 and 80 years are available from the population based cohort known as the study of health in Pomerania (Ship-2 and Ship-Trend). The cross- sectional area of the masseter, medial and lateral pterygoid muscles on both sides of the head will be measured on MRI using the freely available software Osirix. A procedure to standardize the orientation of the MRI images according to Frankfort Horizontal plane has been published by our working group before to guarantee correct reproducible measurements of the muscles.Data on the occlusal contact as classified by the Eichner index will be assembled from the available dental examination data of the study of health in Pomerania (Ship-2 and Ship-Trend)The aims of this study are first to investigate the relationship of TMD signs and symptoms to defined differences in each masticatory muscle thickness, taking occlusal contact and oral parafunctional data into consideration. Second, to investigate of whether these postulated associations differ by gender.

颞下颌关节紊乱病（TMD）患者的咀嚼功能和咬合力受损，但由于牙齿缺失或口腔副功能活动，他们的咀嚼肌对疲劳和萎缩的敏感性尚不确定。研究咬合支持对咀嚼肌及颞下颌关节的影响，探讨不同咬合支持方式，存在于有TMD体征和症状的患者的三块颌肌横截面积上; 2将使用MRI研究咬肌、翼内肌和翼外肌。2440名年龄在20 - 80岁之间的受试者的头部磁共振图像可从称为波美拉尼亚健康研究（Ship-2和Ship-Trend）的基于人群的队列中获得。使用免费软件Osirix在MRI上测量头部两侧咬肌、翼内肌和翼外肌的横截面积。我们的工作组之前已经发布了一个根据法兰克福水平面标准化MRI图像方向的程序，以保证正确的可重复的肌肉测量。根据Eichner指数分类的咬合接触数据将从波美拉尼亚健康研究的可用牙科检查数据中收集（Ship-2和Ship-Trend）本研究的目的是首先调查TMD体征和症状与每个咀嚼肌厚度定义差异的关系，同时考虑咬合接触和口腔功能异常数据。第二，调查这些假设的关联是否因性别而异。