生物応用に向けた常温・常圧・水中ではたらく合成分子モーターの設計と合成

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The synthesis of the new target has been advanced with the formation of the amphiphilic molecular motor functionalized with a chemical tag. As tag, we developed the synthesis of a rhodamine fragment which is very classic to be observed by optical microscopes.Now, just one chemical step is missing to connect the amphiphilic motor with long alkyl chains and the rhodamine fluorescent derivative needed to follow the molecule in the artificial membrane. The coupling was not efficient yet so new connection strategies will be pursued in the next year.