Technical support for mass-spectrometry, protein crystallography and bioinformatics (Z01*)

质谱、蛋白质晶体学和生物信息学的技术支持（Z01*）

• 批准号: 317953636
• 金额: --
• 依托单位: Arbeitsgruppe Strukturbiochemie
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2016
• 资助国家: 德国
• 起止时间: 2015-12-31 至 2019-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/317953636?language=en
• 关键词: Technical; support; mass; spectrometry; protein

Mass-spectrometry, protein crystallography and bioinformatics analysis are important approaches taken in many projects of the Collaborative Research Centres consortium. This service project provides support in these technologies through three Competence Centers of the Philipps-Universität. The Competence Centre for Mass Spectrometry offers multiple services ranging from elemental analysis by ICP-MS, identification and quantification of small molecules and proteins, intact protein-measurement, analysis of post-translational modifications to automated HDX-mass spectrometry. The Competence Centre for Protein Crystallography supports protein production, and provides services in protein crystallization and solving of crystal structures. The Competence Centre for Laboratory Automation and Genomics supports RNAseq experiments and genome re-sequencing. Bioinformatics pipelines for processing and analysis of these data are offered.

质谱分析、蛋白质晶体学和生物信息学分析是合作研究中心联盟许多项目采用的重要方法。该服务项目通过Philipps-Universität的三个能力中心为这些技术提供支持。质谱分析能力中心提供多种服务，从ICP-MS元素分析、小分子和蛋白质的鉴定和定量、完整蛋白质测量、翻译后修饰分析到自动化hdx质谱分析。蛋白质晶体学能力中心支持蛋白质生产，并提供蛋白质结晶和晶体结构解决服务。实验室自动化和基因组学能力中心支持RNAseq实验和基因组重测序。提供了处理和分析这些数据的生物信息学管道。