Development of the fetal therapy using maternal adipose-derived stem cells

使用母体脂肪干细胞开发胎儿疗法

• 批准号: 19K17378
• 负责人: Akihiro Kawashima
• 金额: $ 2.66万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2019
• 资助国家: 日本
• 起止时间: 2019-04-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19K17378/
• 关键词: 胎児治療; ダウン症; 間葉系幹細胞; 脂肪組織由来幹細胞; 精神神経発達遅滞

项目成果

Cytokine profiles in maternal serum are candidates for predicting an optimal timing for the delivery in early‐onset fetal growth restriction

母体血清中的细胞因子谱可用于预测早发性胎儿生长受限的最佳分娩时机

• DOI: 10.1002/pd.5679
• 发表时间: 2020
• 期刊: Prenatal Diagnosis
• 影响因子: 3
• 作者: Kawashima Akihiro;Oba Tomohiro;Yasuhara Rika;Sekiya Bunbu;Sekizawa Akihiko
• 通讯作者: Sekizawa Akihiko

In utero transplantation with organoid of mesenchymal stem cell-derived neural progenitor

间充质干细胞源性神经祖细胞的类器官子宫内移植

• 发表时间: 2020
• 作者: Fukushi Isato;Yokota Shigefumi;Takeda Kotaro;Terada Jiro;Umeda Akira;Yoshizawa Masashi;Kono Yosuke;Hasebe Yohei;Onimaru Hiroshi;Pokorski Mieczyslaw;Okada Yasumasa;Akihiro Kawashima
• 通讯作者: Akihiro Kawashima

Engraftment potential of maternal adipose-derived stem cells for fetal transplantation

• DOI: 10.1016/j.heliyon.2020.e03409
• 发表时间: 2020-03-01
• 期刊: HELIYON
• 影响因子: 4
• 作者: Kawashima, Akihiro;Yasuhara, Rika;Sekizawa, Akihiko
• 通讯作者: Sekizawa, Akihiko

The Engraftment potential of maternal adipose-derived stem cells for fetal transplantation

母体脂肪干细胞用于胎儿移植的植入潜力

• 发表时间: 2019
• 作者: Kikuchi K;Hamano SI;Matsuura R;Nonoyama H;Daida A;Hirata Y;Koichihara R;Hirano D;Ishii A;Hirose S.;宮林 和紀,馬場 洋介,石田 翔二,江原 尚弘,山崎 晋,稲毛 英介,工藤 孝広,大塚 宜一,清水 俊明;Akihiro Kawashima
• 通讯作者: Akihiro Kawashima

Each negative alteration in early-onset fetal growth restriction changes the profile of maternal serum cytokines into a peculiar feature. We want to explore this further as an early warning system.

早发性胎儿生长受限的每一个负面改变都会将母体血清细胞因子的分布改变为一种独特的特征。

• 发表时间: 2019
• 作者: Kawaguchi Shogo;Sakuraba Hirotake;Horiuchi Momone;Ding Jiangli;Matsumiya Tomoh;Seya Kazuhiko;Iino Chikara;Endo Tetsu;Kikuchi Hidezumi;Yoshida Shukuko;Hiraga Hiroto;Fukuda Shinsaku;Imaizumi Tadaatsu;今孝志，佐々木悠，阿部靖彦，小野里祐介，佐藤秀則，矢尾板孝夫，八木周，水本尚子，東海林正邦，堺貴之，小関歩，上野義之;Akihiro Kawashima
• 通讯作者: Akihiro Kawashima