Discovery of a novel anti-aging target by researching chronic infectious disease

通过研究慢性传染病发现新的抗衰老靶点

• 批准号: 19K21582
• 负责人: MAEKAWA YOICHI
• 金额: $ 4.16万
• 依托单位: Gifu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Research (Exploratory)
• 财政年份: 2019
• 资助国家: 日本
• 起止时间: 2019-06-28 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19K21582/
• 关键词: 慢性炎症; 免疫回避; 抗炎症; 慢性感染; 旋毛虫由来因子; 炎症抑制; 病原体由来抗炎症分子; SASP; 寄生虫感染; 慢性感染症; 旋毛虫

项目成果

NEUTROPHIL ELASTASE INHIBITION AMELIORATES ENDOTOXIN-INDUCED MYOCARDIAL INJURY ACCOMPANYING DEGRADATION OF CARDIAC CAPILLARY GLYCOCALYX

• DOI: 10.1097/shk.0000000000001482
• 发表时间: 2020-09-01
• 期刊: SHOCK
• 影响因子: 3.1
• 作者: Fukuta, Tetsuya;Okada, Hideshi;Ogura, Shinji
• 通讯作者: Ogura, Shinji

Trichinella and Trichinelllosis

旋毛虫和旋毛虫病

• 发表时间: 2021
• 作者: Wu Zhiliang;Nagano Isaoa;Khueangchiangkhwang Sukhonthipa;Maekawa Yoichi
• 通讯作者: Maekawa Yoichi

Role of extracellular vesicles from parasitic nematode, Trichinella spiralis

寄生线虫旋毛虫​​细胞外囊泡的作用

• 发表时间: 2021
• 作者: Sukhonthip Khueangchiangkhwang;Zhiliang Wu;Yoichi Maekawa
• 通讯作者: Yoichi Maekawa

Glucose transporter Glut1 controls diffuse invasion phenotype with perineuronal satellitosis in diffuse glioma microenvironment.

• DOI: 10.1093/noajnl/vdaa150
• 发表时间: 2021-01
• 期刊: Neuro-oncology advances
• 作者: Miyai M;Kanayama T;Hyodo F;Kinoshita T;Ishihara T;Okada H;Suzuki H;Takashima S;Wu Z;Hatano Y;Egashira Y;Enomoto Y;Nakayama N;Soeda A;Yano H;Hirata A;Niwa M;Sugie S;Mori T;Maekawa Y;Iwama T;Matsuo M;Hara A;Tomita H
• 通讯作者: Tomita H

Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model

• DOI: 10.1016/j.isci.2019.08.033
• 发表时间: 2019-08
• 期刊: iScience
• 影响因子: 5.8
• 作者: S. Nishide;S. Matsunaga;M. Shiota;Takehiro Yamaguchi;S. Kitajima;Y. Maekawa;Norihiko Takeda;M. Tomura;J. Uchida;K. Miura;T. Nakatani;S. Tomita