Konfokales Lasermikroskop

我们研究人类罕见的血液和免疫系统疾病，旨在揭示造血和免疫的分子机制。我们对研究先天免疫细胞内的细胞内运输动力学特别感兴趣。为了分析和量化这些复杂而快速的过程，最先进的高分辨率激光共聚焦显微镜可以进行活细胞成像，这是必不可少的核心设备。2015年夏天，KUBUS研究中心的一台基本共聚焦显微镜与Ensenauer教授的团队一起搬到了德<s:1>塞尔多夫大学。属于AG Endres的基本共聚焦显微镜是可用的，但这种显微镜被大量使用，没有配备高灵敏度的探测器。然而，为了推进我们正在进行和计划中的项目（由DFG， ERC， BMBF和其他机构资助），额外的显微镜时间和提供最新技术进步的设备，高分辨率能力和最佳检测器质量是必不可少的先决条件。不仅申请人，而且来自KUBUS研究中心代表的各个学科的共同申请人都依赖并将从显微镜中获得高额利润。

We study human rare diseases of the blood and the immune system with the aim to reveal molecular mechanisms of haematopoiesis and immunity. We are particularly interested in investigating the dynamics of intracellular transport within innate immune cells. To analyse and quantify these complex and rapid processes, a state-of-the-art high-resolution laser-confocal microscope with the possibility to perform live-cell imaging constitutes an essential core equipment. In summer 2015, a basic confocal microscope that had been present in the KUBUS Research Center was moved to the University of Düsseldorf together with the group of Prof. Ensenauer. A basic confocal microscope belonging to AG Endres is available, yet this microscope is heavily used and is not equipped with high sensitivity detectors. However, to advance our ongoing and planned projects (funded by DFG, ERC, BMBF and others), additional microscope time and a device offering the latest technical advancements, high resolution capacities and optimal detector quality are indispensable prerequisites. Not only the applicant, but also the co-applicants from across the disciplines represented in the KUBUS Research Center depend on and will highly profit from the microscope.