SFB 1319: Extreme light for sensing and driving molecular chirality (ELCH)

SFB 1319：用于传感和驱动分子手性的极光 (ELCH)

• 批准号: 328961117
• 金额: --
• 依托单位: Freie Universität Berlin
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/328961117?language=en
• 关键词: SFB; 1319; Extreme; light; sensing

Molecular chirality – the fact that left-handed and right-handed versions of a molecule share almost all of their physical properties yet differ dramatically in their chemical and biological behavior – poses intellectual challenges across the natural sciences. For example, molecular chirality is relevant to the building blocks of life and plays a vital role in medicine and health. Our CRC focuses on a different yet equally fundamental aspect. With ELCH, we have established a center of research targeting a microscopic and quantum me-chanical understanding of chiral molecules in the gas phase. To this end, the most advanced tools of experimental and theoretical atomic and molecular physics, as well as quantum optics (AMO), are used to control and drive chirality at the isolated single-molecule level. Using electromagnetic radiation, we address the entire molecular system consisting of electrons and nuclei and provide a unique light-driven gas-phase laboratory for chiral molecular physics. In the first funding period, ELCH has fostered more than 40 collaborations, which have resulted in several important achievements towards four long-term goals: (i) Combination of partial Coulomb explosion with photo-electron diffraction is a breakthrough towards the determination of absolute configuration, allowing to target larger molecules. (ii) A high-resolution laser-based method has been realized as part of a set of advanced instruments for the determination of enantiomeric excess. It is applicable to mixtures and con-formers and may change the routine instrumentation for chemists. (iii) Enantiomer-selective excitation of a racemate is a key prerequisite for chiral purification, and a seminal experimental demonstration has been complemented by a theoretical proposal for achieving complete selectivity. (iv) Demonstration of laser spectroscopy of short-lived radioactive molecules using the RaF prototype opens new perspectives for fundamental physics experiments since parity-violating interactions in chiral molecules increase steeply in strength with the atomic number.Besides our scientific aims, we pursue three further key goals within this CRC. Our strategic goal is to strengthen AMO physics in Kassel and at the participating institutions. For the second funding period, the core AMO competence in Kassel is reinforced by two new projects – one based on a recent W2 appoint-ment and one fostering independence of a young researcher. Our educational goal is to provide the best possible training for students and PostDocs in a highly dynamic area of AMO science. To fascinate pupils and draw them to the natural sciences, we will implement a transfer project to develop modern teaching material for schools to be distributed nationwide. Our gender equality goal takes advantage of the existing infrastructure at Universität Kassel and our partner institutions, already at a high level, and substantiates it by physics-specific components.

分子手性--左手和右手分子几乎拥有所有的物理性质，但在化学和生物学行为上却有着巨大的差异--在自然科学领域提出了智力挑战。例如，分子手性与生命的构建单元相关，并且在医学和健康中起着至关重要的作用。我们的CRC侧重于一个不同但同样重要的方面。通过ELCH，我们已经建立了一个研究中心，目标是对气相中手性分子的微观和量子力学理解。为此，最先进的实验和理论原子和分子物理学工具，以及量子光学（AMO），被用来控制和驱动在孤立的单分子水平的手性。使用电磁辐射，我们解决了由电子和原子核组成的整个分子系统，并为手性分子物理提供了一个独特的光驱动气相实验室。在第一个资助期内，ELCH已促成超过40项合作，并在四个长期目标方面取得了多项重要成果：（i）部分库仑爆炸与光电子衍射的结合是确定绝对构型的突破，允许针对更大的分子。(ii)一个高分辨率的激光为基础的方法已经实现了一套先进的仪器的一部分，用于测定对映体过量。它适用于混合物和构象异构体，并可能改变化学家的常规仪器。(iii)外消旋体的对映体选择性激发是手性纯化的关键先决条件，一个开创性的实验证明已经得到了实现完全选择性的理论建议的补充。(iv)使用RaF原型的短寿命放射性分子的激光光谱演示为基础物理实验开辟了新的视角，因为手性分子中的宇称破坏相互作用的强度随着原子序数的增加而急剧增加。除了我们的科学目标外，我们还追求本CRC中的三个关键目标。我们的战略目标是加强卡塞尔和参与机构的AMO物理学。在第二个资助期，卡塞尔的AMO核心能力通过两个新项目得到加强-一个是基于最近的W2计划，另一个是促进年轻研究人员的独立性。我们的教育目标是在AMO科学的高度动态领域为学生和博士后提供最好的培训。为了吸引学生并吸引他们学习自然科学，我们将实施一个转让项目，为学校编写现代教材，并在全国范围内分发。我们的性别平等目标利用了卡塞尔大学和我们的合作机构现有的基础设施，已经处于高水平，并通过物理特定组件来充实它。