Directed Evolution of a Palette of Optogenetic Indicators for Multiplexed Imaging of Cellular Metabolism
Directed Evolution of a Palette of Optogenetic Indicators for Multiplexed Imaging of Cellular Metabolism
批准号:
19H00920
负责人:
キャンベル ロバート.アール
金额:
$29.95万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2019
资助国家:
日本
项目状态:
已结题
起止时间:
2019-04-01 至 2020-03-31
中文摘要
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英文摘要
The goal of this project was to perform "Directed Evolution of a Palette of Optogenetic Indicators for Multiplexed Imaging of Cellular Metabolism" by using the Grant-in-Aid for Scientific Research (A). In this fiscal year, this grant enabled us to set up the laboratory for the study mentioned above. For example, we purchased a wide-field fluorescence microscopy, which Campbell lab is using to accelerate the development of a range of optogenetic indicators.
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Genetically Encoded Tools [Fluorophores] and their Applications
基因编码工具[荧光团]及其应用
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[Y. Shen, S.-Y. Wu, Y. Wen, M. J. Lemieux, and R. E. Campbell, R. E. Campbell, R. E. Campbell, Y. Li and R. E. Campbell, R. E. Campbell]
通讯作者:
R. E. Campbell
Genetically encoded fluorescent probes for multi-parameter imaging of cell signalling and metabolism
用于细胞信号传导和代谢多参数成像的基因编码荧光探针
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[Robert E. Campbell]
通讯作者:
Robert E. Campbell
Genetically-encoded red and near-infrared neural activity indicators and new indicator development
基因编码的红色和近红外神经活动指标和新指标开发
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[笠原遥太郎, 武田貴志, 星野哲久, 久木一朗, 芥川智行, Robert E. Campbell]
通讯作者:
Robert E. Campbell
Protein engineering and directed evolution for the creation of optogenetic indicators
用于创建光遗传学指标的蛋白质工程和定向进化
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[唐 睿, 西川 銀河, 吉井 丈晴, 京谷 隆, 西原 洋知, Robert E. Campbell]
通讯作者:
Robert E. Campbell
Metabolismの「非」常識を検証する -近赤外蛍光乳酸センサーの開発-
验证新陈代谢的“不寻常”常识 - 近红外荧光乳酸传感器的开发 -
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[X. Lu, Y. Wen, W. Zhang, M. J. Lemieux, and R. E. Campbell, Y. Nasu and R. E. Campbell, R. E. Campbell, R. E. Campbell, Y. Nasu and R. E. Campbell]
通讯作者:
Y. Nasu and R. E. Campbell
共 19 条
Massive Expansion of the Palette of Fluorescent Protein-based Sensors for Multiplexed Imaging of Signaling and Metabolism
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批准号:24H00489
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$31.2万
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财政年份:2024
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负责人:キャンベル ロバート.アール
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依托单位:
Directed Evolution of a Palette of Optogenetic and Chemi-Optogenetic Indicators for Multiplexed Imaging of Cellular Metabolism
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批准号:19H05633
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$128.96万
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财政年份:2019
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负责人:キャンベル ロバート.アール
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依托单位:
海外基金