The inhibition of muscle disuse atrophy in burrowing frogs

由于肢体不动、长期卧床或太空旅行而导致的长期肌肉废用可导致病理变化，从而导致肌肉萎缩。 通过研究一种独特的澳大利亚青蛙，这种青蛙在地下打洞并保持不动9-12个月，并且没有显示肌肉萎缩，我们将大大推进我们对抑制肌肉萎缩的生理机制的理解。 进行这项研究的好处将包括： - 了解抗氧化剂和内源性阿片类药物在减少肌肉萎缩中的作用 - 研究生培养 - 促进昆士兰州大学和CSIRO畜牧业之间的合作。

Prolonged muscle disuse, as a consequence of limb immobilisation, extended bed-rest or space travel, can lead to pathological changes resulting in muscle wasting. By examining a unique Australian frog that burrows underground and remains immobile for 9-12 months, and which shows no muscle wasting, we will significantly advance our understanding of the physiological mechanisms that inhibit muscle atrophy. Benefits of conducting this research will include: - understanding the role of antioxidants and endogenous opioids in reducing muscle wasting - training of postgraduate students - stimulating collaboration between The University of Queensland and CSIRO Livestock Industries.