GRK 2433: Differential Equation- and Data-driven Models in Life Sciences and Fluid Dynamics (DAEDALUS)
GRK 2433:生命科学和流体动力学中的微分方程和数据驱动模型(DAEDALUS)
基本信息
- 批准号:384950143
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:德国
- 项目类别:Research Training Groups
- 财政年份:2018
- 资助国家:德国
- 起止时间:2017-12-31 至 2022-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Due to the massive complexity of physical and engineering systems, traditional modeling based on differential equations (DE-based modeling) today is often no longer capable of providing sufficiently adequate mathematical models, for instance for simulations. One particularly promising way to address this challenge is the incorporation of data measured from the real-world system into the model. One key question in this process, which is still wide open, is the optimal balance between data-adaptiveness in the sense of infusing information from a measured data set into the modeling process and more traditional DE-based modeling. Evidently, this question can only be satisfactorily answered by a combined viewpoint from both the mathematical side and the application side. Consequently, our RTG team is highly interdisciplinary and includes computer scientists, engineers, mathematicians, and physicists. We will focus on two main areas: (1) Life sciences, which typically rely heavily on real-world data, and (2) fluid dynamics, where traditionally DE-based modeling plays a major role. The mission of our RTG is three-fold: First, the cohort will be trained in the necessary mathematical techniques such as data assimilation, machine learning, mathematical modeling, model reduction, sparse/low-rank methods, and uncertainty quantification. This will be achieved by an ‘Introductory Intensive Course Period’, advanced training components, and annual winter schools. Second, each PhD student will learn to communicate and collaborate in an interdisciplinary team. This training will begin in the ‘Interdisciplinary Welcome Week’, and continue with the interdisciplinary PI team heading each project and special events such as research retreats. Third, the range of projects will provide a multitude of viewpoints on the interplay between incorporation of data and DE-based modeling, thereby contributing to developing a deep understanding of the optimal balance between data and models and attacking the challenge of the optimal degree of data-adaptiveness in the modeling process from different angles. The research experience of the PhD students will be rounded off by international interaction and various activities in the rich Berlin scientific landscape. Consequently, our RTG will educate a new generation of interdisciplinary researchers who are highly trained in data science as well as more traditional mathematical modeling and simulation.
由于物理和工程系统的巨大复杂性,基于微分方程的传统建模(基于DE的建模)今天通常不再能够提供足够充分的数学模型,例如用于仿真。解决这一挑战的一个特别有希望的方法是将从现实世界系统中测量的数据纳入模型。这个过程中的一个关键问题,这仍然是开放的,是数据自适应性之间的最佳平衡,在这个意义上注入信息从测量数据集到建模过程和更传统的基于DE的建模。显然,这个问题只能从数学方面和应用方面的综合观点得到满意的回答。因此,我们的RTG团队是高度跨学科的,包括计算机科学家,工程师,数学家和物理学家。我们将专注于两个主要领域:(1)生命科学,通常严重依赖于真实世界的数据,以及(2)流体动力学,传统的基于DE的建模起着重要作用。我们的RTG的使命有三个方面:首先,队列将接受必要的数学技术培训,如数据同化,机器学习,数学建模,模型简化,稀疏/低秩方法和不确定性量化。这将通过“入门强化课程”、高级培训部分和年度冬季学校来实现。其次,每个博士生将学习在跨学科团队中进行沟通和合作。该培训将在“跨学科欢迎周”开始开始,并继续与跨学科PI团队领导每个项目和特殊活动,如研究务虚会。第三,项目范围将提供关于数据整合和基于DE的建模之间相互作用的多种观点,从而有助于深入理解数据和模型之间的最佳平衡,并从不同角度应对建模过程中数据适应性的最佳程度的挑战。博士生的研究经验将通过国际互动和丰富的柏林科学景观中的各种活动来完成。因此,我们的RTG将教育新一代的跨学科研究人员,他们在数据科学以及更传统的数学建模和仿真方面训练有素。
项目成果
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其他文献
Internet-administered, low-intensity cognitive behavioral therapy for parents of children treated for cancer: A feasibility trial (ENGAGE).
针对癌症儿童父母的互联网管理、低强度认知行为疗法:可行性试验 (ENGAGE)。
- DOI:
10.1002/cam4.5377 - 发表时间:
2023-03 - 期刊:
- 影响因子:4
- 作者:
- 通讯作者:
Differences in child and adolescent exposure to unhealthy food and beverage advertising on television in a self-regulatory environment.
在自我监管的环境中,儿童和青少年在电视上接触不健康食品和饮料广告的情况存在差异。
- DOI:
10.1186/s12889-023-15027-w - 发表时间:
2023-03-23 - 期刊:
- 影响因子:4.5
- 作者:
- 通讯作者:
The association between rheumatoid arthritis and reduced estimated cardiorespiratory fitness is mediated by physical symptoms and negative emotions: a cross-sectional study.
类风湿性关节炎与估计心肺健康降低之间的关联是由身体症状和负面情绪介导的:一项横断面研究。
- DOI:
10.1007/s10067-023-06584-x - 发表时间:
2023-07 - 期刊:
- 影响因子:3.4
- 作者:
- 通讯作者:
ElasticBLAST: accelerating sequence search via cloud computing.
ElasticBLAST:通过云计算加速序列搜索。
- DOI:
10.1186/s12859-023-05245-9 - 发表时间:
2023-03-26 - 期刊:
- 影响因子:3
- 作者:
- 通讯作者:
Amplified EQCM-D detection of extracellular vesicles using 2D gold nanostructured arrays fabricated by block copolymer self-assembly.
使用通过嵌段共聚物自组装制造的 2D 金纳米结构阵列放大 EQCM-D 检测细胞外囊泡。
- DOI:
10.1039/d2nh00424k - 发表时间:
2023-03-27 - 期刊:
- 影响因子:9.7
- 作者:
- 通讯作者:
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{{ truncateString('', 18)}}的其他基金
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2901954 - 财政年份:2028
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Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
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- 批准号:
2896097 - 财政年份:2027
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A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
- 批准号:
2780268 - 财政年份:2027
- 资助金额:
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Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
- 批准号:
2908918 - 财政年份:2027
- 资助金额:
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Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
- 批准号:
2908693 - 财政年份:2027
- 资助金额:
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Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
- 批准号:
2908917 - 财政年份:2027
- 资助金额:
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Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
- 批准号:
2879438 - 财政年份:2027
- 资助金额:
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Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
- 批准号:
2890513 - 财政年份:2027
- 资助金额:
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Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
- 批准号:
2876993 - 财政年份:2027
- 资助金额:
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Research Units