Asymmetric Synthesis and Biological Evaluation of Bioactive Alkaloids and their Analogues

生物活性生物碱及其类似物的不对称合成及生物学评价

• 批准号: DP0665752
• 负责人: Em/Prof Stephen Pyne
• 金额: $ 26.68万
• 依托单位: University of Wollongong
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0665752
• 关键词: Asymmetric; Synthesis; Biological; Evaluation; Bioactive

We propose to develop innovative methods for preparing bioactive natural products and their analogues with potential applications as new and safer therapeutic drugs and agricultural chemicals. This project would make important scientific contributions to the advancement of the fundamentals of synthetic organic chemistry and contribute to Australia's development as a knowledge-based economy. The methodology and products developed may have potential pharmaceutical and agricultural applications from which the country could benefit from in the future. This project would help developed skilled people that may develop innovative outcomes in the future, especially in the developing pharmaceutical and biotechnology industries in Australia.

我们建议开发新的方法来制备具有生物活性的天然产物及其类似物，作为新的和更安全的治疗药物和农用化学品的潜在应用。 这一项目将为推进合成有机化学的基本原理作出重要的科学贡献，并为澳大利亚作为知识型经济的发展作出贡献。 所开发的方法和产品可能具有潜在的制药和农业应用，该国今后可从中受益。该项目将帮助开发有技能的人，他们可能在未来开发创新成果，特别是在澳大利亚发展中的制药和生物技术行业。