Neural correlates of body dissatisfaction: A Functional MRI study.

身体不满意的神经相关性：功能性 MRI 研究。

• 批准号: 23659390
• 负责人: KODAMA NAOKI
• 金额: $ 2.25万
• 依托单位: University of Occupational and Environmental Health, Japan
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23659390/
• 关键词: 摂食障害; 体形の不満; 機能画像; 神経性食欲不振症; ストレス

Eating disorders are disorders of unknown etiology that tend to affect young women. Body dissatisfaction is an important factor in anorexia nervosa (AN). However, the functional neuroanatomy of body dissatisfaction in AN is largely unknown. This study has investigated body-shape comparison to establish neural correlates of body dissatisfaction in patients with AN.In the recovered AN group the body-shape comparison induced more activation of the left lingual gyrus, left fusiform body area and left amygdala when subjects compared their own body-shape with images of slim female bodies. The visual cortex responses reflect their concern about the bodies of others. Brain networks associated with anxiety that was induced by self-comparison to others' images may be involved in their hidden remaining body dissatisfaction and hence with the high relapse rate of eating disorders. The results are be helpful in that they shed light on the biological pathology of patients with eating disorders.

进食障碍是一种病因不明的疾病，往往会影响年轻女性。身体不满意是神经性厌食症（AN）的重要因素。然而，AN中身体不满的功能神经解剖学在很大程度上是未知的。本研究调查了体形比较，以建立神经相关的身体不满的患者AN。在恢复AN组的体形比较诱导更多的激活左舌回，左梭状体区和左杏仁核时，受试者比较自己的体形与苗条的女性身体的图像。视觉皮层的反应反映了他们对他人身体的关注。与焦虑相关的大脑网络是由自我比较他人的形象引起的，可能与他们隐藏的剩余身体不满有关，因此与饮食失调的高复发率有关。这些结果有助于阐明进食障碍患者的生物病理学。

项目成果

機能画像を使った， 体形の不満に関する研究

利用功能图像研究体型不满

• 作者: Naoki Kodama;Yoshiya Moriguchi;Motonari Maeda;Tetsuya Ando;Hiroe Kikuchi;Takashi Hamada;Gen Komaki;Naoki Kodama;兒玉直樹，守口善也，安藤哲也，菊地裕絵，小牧 元
• 通讯作者: 兒玉直樹，守口善也，安藤哲也，菊地裕絵，小牧 元

機能画像を使った，体形の不満に関する研究

利用功能图像研究体型不满

• 发表时间: 2013
• 作者: Naoki Kodama;Yoshiya Moriguchi;Motonari Maeda;Tetsuya Ando;Hiroe Kikuchi;Naoki Akamatsu;Tsuji Sadatoshi;Gen Komaki;兒玉直樹，守口善也，小牧元,辻貞俊
• 通讯作者: 兒玉直樹，守口善也，小牧元,辻貞俊

Neural correlates of body comparison and weight estimation in weight-recovered anorexia nervosa: a functional magnetic resonance imaging study.

• DOI: 10.1186/s13030-018-0134-z
• 发表时间: 2018
• 期刊: BioPsychoSocial medicine
• 影响因子: 2.1
• 作者: Kodama N;Moriguchi Y;Takeda A;Maeda M;Ando T;Kikuchi H;Gondo M;Adachi H;Komaki G
• 通讯作者: Komaki G

Neural correlates of body dissatisfaction : A Functional MRI study

身体不满意的神经相关性：功能性 MRI 研究

• 发表时间: 2012
• 作者: Naoki Kodama;Yoshiya Moriguchi;Motonari Maeda;Tetsuya Ando;Hiroe Kikuchi;Naoki Akamatsu;Tsuji Sadatoshi;Gen Komaki;兒玉直樹，守口善也，小牧元,辻貞俊;Naoki Kodama
• 通讯作者: Naoki Kodama