Exploration of cause of death and acute phase treatment for carbondioxide poisoning

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The hazardousness is recognized in CO2 poisoning by real cases and disasters, however the mechanism and the direct cause of CO2 poisoning death are not revaeled. To investigate the cause of death, we established model rats and time-dependently measured hemodynamics, blood gas analysis in rats and theconcentration of CO2 and O2 in the chamber. After the sacrifice, we isolated the tissues and analyzed some molecular biological data. This study is very challenging for us to aim to determine the upper limitation of CO2 concentration in the blood and elucidate the mechanism of CO2 poisoning.