Real-time Observation of Dynamics of Vitreous Body

从猪玻璃体散射光的动态观察，强度自相关函数，揭示了两个扩散系数，D（快）和D（慢），得到。 我们发展了描述玻璃体凝胶系统中实体密度波动的理论，其中透明质酸钠聚合物填充在胶原纤维网络的网格中。胶原和透明质酸钠的动力学解释了波动的两种弛豫模式。从D（快）和D（慢）获得的胶原扩散系数非常接近于在水溶液中的扩散系数，这表明玻璃体处于溶胀状态。扩散系数被认为是依赖于位置（表面或中心部分）的玻璃体从散射光采样。 提示玻璃体内玻璃酸钠和胶原分布不均匀，玻璃体呈壳状结构。

From the observations of the dynamics of light scattered by the pig vitreous body, intensity autocorrelation functions that revealed two diffusion coefficients, D(fast) and D(slow), were obtained. We developed the theory for describing the density fluctuation of the entities in the vitreous gel system with Na-hyaluronate polymers filled in the meshes of collagen fiber network. The dynamics of collagen and Na-hyaluronate explains two relaxation modes of the fluctuation. The diffusion coefficient of collagen obtained from D(fast) and D(slow) is very close to that in aqueous solution, which suggests the vitreous body is in the swollen state. The diffusion coefficients were found to be dependent on the position (surface or central part) of the vitreous body from which the scattered light sampled. The inhomogeneous distribution of Na-hyaluronate and collagen and the shell structure of the vitreous body were suggested.