Involvement of maternal mRNA in the regulation of differentiation during preimplantation development.
Involvement of maternal mRNA in the regulation of differentiation during preimplantation development.
批准号:
24658244
负责人:
AOKI Fugaku
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
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英文摘要
To identify the maternal mRNA that are involved in the differentiation during preimplantation development, I conducted RNA sequencing analysis using the oocytes and embryos. The results showed that although 70% of maternal mRNAs were degraded soon after fertilization, the rest of them survived this wave of a rapid degradation. Especially, those from 691 genes were hardly degraded during the 1-cell stage. Gene Ontology (GO) enrichment analysis revealed that these genes were enriched in the GO terms categorized into transcription.
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
マウス受精前後における母性mRNA分解に関する網羅的な動態解析
小鼠受精前后母体mRNA降解的综合动力学分析
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[金綾奈, 鈴木元, 阿部健一郎, 青木不学]
通讯作者:
青木不学
RNAシーケンスによるマウス一細胞期胚の遺伝子発現解析
通过 RNA 测序对小鼠单细胞阶段胚胎进行基因表达分析
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[阿部健一郎, 山本龍馬, 曹旻君, 鈴木穣, 青木不学]
通讯作者:
青木不学
Involvement of histone variants in the reprogramming of gene expression before and after fertilization
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批准号:18H03970
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$28.37万
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财政年份:2018
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负责人:AOKI Fugaku
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依托单位:
Identification and analysis for the function of maternal factors using CRISPR/Cas system
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批准号:26660246
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2014
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负责人:AOKI Fugaku
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依托单位:
Mechanism for the acquisition of totipotency by Yamanaka factors
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批准号:22658091
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.32万
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财政年份:2010
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负责人:AOKI Fugaku
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依托单位:
Acquisition of the meiotic and mitotic competence during oocyte growth
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批准号:22380156
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.73万
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财政年份:2010
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负责人:AOKI Fugaku
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依托单位:
Mechanism for the reprogramming of gene expression in the oocytes and preimplantation embryos
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批准号:17380166
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.04万
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财政年份:2005
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负责人:AOKI Fugaku
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依托单位:
Mechanism of the reprogramming of gene expression in mammalian oocytes
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批准号:14360164
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.47万
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财政年份:2002
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负责人:AOKI Fugaku
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依托单位:
Regulation of zygotic gene activation in mammals.
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批准号:10660266
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1998
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负责人:AOKI Fugaku
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依托单位:
海外基金