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Involvement of maternal mRNA in the regulation of differentiation during preimplantation development.

Involvement of maternal mRNA in the regulation of differentiation during preimplantation development.
母体 mRNA 参与植入前发育过程中分化的调节。
批准号:
24658244
负责人:
AOKI Fugaku
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31

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中文摘要
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英文摘要
To identify the maternal mRNA that are involved in the differentiation during preimplantation development, I conducted RNA sequencing analysis using the oocytes and embryos. The results showed that although 70% of maternal mRNAs were degraded soon after fertilization, the rest of them survived this wave of a rapid degradation. Especially, those from 691 genes were hardly degraded during the 1-cell stage. Gene Ontology (GO) enrichment analysis revealed that these genes were enriched in the GO terms categorized into transcription.
期刊论文(2)
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会议论文
マウス受精前後における母性mRNA分解に関する網羅的な動態解析
小鼠受精前后母体mRNA降解的综合动力学分析
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [金綾奈, 鈴木元, 阿部健一郎, 青木不学]
通讯作者: 青木不学
RNAシーケンスによるマウス一細胞期胚の遺伝子発現解析
通过 RNA 测序对小鼠单细胞阶段胚胎进行基因表达分析
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [阿部健一郎, 山本龍馬, 曹旻君, 鈴木穣, 青木不学]
通讯作者: 青木不学
Involvement of histone variants in the reprogramming of gene expression before and after fertilization
  • 批准号:
    18H03970
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
  • 资助金额:
    $28.37万
  • 财政年份:
    2018
  • 负责人:
    AOKI Fugaku
  • 依托单位:
Identification and analysis for the function of maternal factors using CRISPR/Cas system
  • 批准号:
    26660246
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.5万
  • 财政年份:
    2014
  • 负责人:
    AOKI Fugaku
  • 依托单位:
Mechanism for the acquisition of totipotency by Yamanaka factors
  • 批准号:
    22658091
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.32万
  • 财政年份:
    2010
  • 负责人:
    AOKI Fugaku
  • 依托单位:
Acquisition of the meiotic and mitotic competence during oocyte growth
  • 批准号:
    22380156
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $12.73万
  • 财政年份:
    2010
  • 负责人:
    AOKI Fugaku
  • 依托单位:
海外基金