骨质疏松症免疫学危险因素的探讨-猫眼课题宝

骨质疏松症免疫学危险因素的探讨

批准号：

24659298

负责人：

NAKAMURA Kazutoshi

金额：

$2.58万

依托单位：

Niigata University

依托单位国家：

日本

项目类别：

Grant-in-Aid for Challenging Exploratory Research

财政年份：

2012

资助国家：

日本

项目状态：

已结题

起止时间：

2012-04-01 至 2014-03-31

来源：

https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-24659298/

关键词：

免疫骨粗鬆症疫学研究骨密度抗体加齢骨代謝炎症リスク要因

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英文摘要

The aim of the study was to explore potential risk factors for osteoporosis and its related health conditions in epidemiologic studies. Immunological and inflammation markers in serum were measured, and their associations with bone mass and cognitive function were tested. Serum Cytomegalovirus antibody titers were significantly correlated with spinal bone mineral density in the Yokogoshi Study (r=-0.12), and Cytomegalovirus antibody titers were significantly correlated with 2-year changes in Mini-Mental State Examination scores in the Yamato Study (r=0.30). It is concluded that previous viral infection could predict osteoporosis and/or cognitive decline.

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