Randomized controlled trial of calcium supplementation

补钙的随机对照试验

• 批准号: 20390183
• 负责人: NAKAMURA Kazutoshi
• 金额: $ 11.9万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20390183/
• 关键词: 保健栄養; 介入研究; 骨粗鬆症; 骨密度; ランダム化比較試験; カルシウム; 女性; 予防医学; 栄養; 骨代謝

The aim of this study was to reveal a possible effect of calcium supplementation on bone loss of postmenopausal women. Four-hundred fifty women were divided into the following three groups : 1) receiving 500 mg/day of calcium supplement, 2) receiving 250 mg/day of calcium supplement, and 3) placebo. Loss of bone mineral density in femoral neck and lumbar spine for two years was compared among the three groups. Bone loss of lumbar spine in the two calcium supplement groups was significantly smaller than the placebo group. A calcium supplement 250 mg/day prevents spinal bone loss of Japanese women.

本研究的目的是揭示补钙对绝经后妇女骨质流失的可能影响。 450 名女性被分为以下三组：1）接受 500 毫克/天的钙补充剂，2）接受 250 毫克/天的钙补充剂，以及 3）安慰剂。比较三组两年内股骨颈和腰椎骨矿物质密度的损失。两个补钙组的腰椎骨质流失明显小于安慰剂组。日本女性每天补充 250 毫克钙可预防脊柱骨质流失。

项目成果

ホームページ等。

主页等

日本人のカルシウム摂取と骨の健康(日本でのデータを中心に)

日本人的钙摄入量与骨骼健康（主要数据来自日本）

• 发表时间: 2009
• 作者: Nishimura Y;Kumagai N;Maeda M;Hayashi H;Fukuoka K;nakano T;Miura Y;HIratsuka J;Otsuki T.;中村和利
• 通讯作者: 中村和利

Low calcium intake is associated with increased bone resorption in postmenopausal Japanese women: Yokogoshi Study

• DOI: 10.1017/s1368980009005084
• 发表时间: 2009-12-01
• 期刊: PUBLIC HEALTH NUTRITION
• 影响因子: 3.2
• 作者: Nakamura, Kazutoshi;Saito, Toshiko;Yamamoto, Masaharu
• 通讯作者: Yamamoto, Masaharu