Development of a novel revascularization method to treat diffuse coronary artery diseases with transplantation of artery and adipose tissues
Development of a novel revascularization method to treat diffuse coronary artery diseases with transplantation of artery and adipose tissues
批准号:
24659392
负责人:
SATA Masataka
金额:
$2.41万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012 至 --
中文摘要
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英文摘要
To elucidate the pathophysiology of human diffuse coronary atherosclerotic lesions, we analyzed the endarterectomy samples obtained during cardiac bypass surgery. We found enhanced infiltration of inflammatorycells such as macrophages and T cells not only in vessel wall but also in perivascular adipose tissues. These chronic inflammation was associated with augmented angiogenesis. Based on this observation, we started to develop a novel revascularization method to treat diffuse coronary artery diseases with transplantation of own artery and adipose tissues.
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发表时间:
2012
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[添木武, 佐田政隆, 田中君枝, 島袋充生]
通讯作者:
島袋充生
徳島大学大学院ヘルスバイオサイエンス研究部循環器内科学
德岛大学健康生物科学研究生院心血管内科
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共 101 条
Novel mechanism of chronic inflammation in progression and destabilization of atherosclerotic plaque
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批准号:19H03654
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2019
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负责人:SATA Masataka
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依托单位:
A study to elucidate the mechanism by which sterile chronic inflammation occurs in arterial wall and perivascular adipose tissue
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批准号:16H05299
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2016
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负责人:SATA Masataka
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依托单位:
Development of therapies for severe ischemic cardiomyopathy to substute heart transplantation
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批准号:25670390
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2013
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负责人:SATA Masataka
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依托单位:
Visualization of chronic inflammation in arterial wall and perivascular adipose tissue
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批准号:25293184
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
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财政年份:2013
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负责人:SATA Masataka
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依托单位:
Development of a novel treatment for coronary artery diseases by replacement of the epicardial adipose tissue
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批准号:23659420
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2011
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依托单位:
Elucidation of molecular mechanism of plaque destabilization and identification of predictable factors for acute coronary syndrome
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批准号:22390159
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
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财政年份:2010
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负责人:SATA Masataka
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依托单位:
Identification of novel regulator of atherosclerosis and development of molecular imaging technique
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批准号:19390207
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.15万
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财政年份:2007
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负责人:SATA Masataka
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依托单位:
Idermfiration and Charactetizaiion of Bone Marrow-derived Vascular Progenitor Cells
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批准号:15390241
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.6万
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负责人:SATA Masataka
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依托单位: