Study on new tumor imaging by cell labelling method

近年来完成了具有癌细胞特异性吸引特性的特殊T细胞“HOZOT细胞”的报道。利用HOZOT细胞，我们开发了一种针对特定癌症的核医学诊断方法，本研究旨在将其应用于核医学治疗癌症。我们成功地用铟-111标记了HOZOT细胞，我给患有人类乳腺癌的小鼠静脉注射了这种药物，我们用动物SPECT-CT设备对它们进行了成像，但不幸的是，HOZOT细胞的积累只在整个双肺中弥漫性地看到，对癌症组织没有什么有意义的积累。我们可以用除铟-111以外的核素来标记HOZOT细胞，并希望将来能够用它们来成像癌症。

In late years the report about special T cell "HOZOT cell" with the property that a cancer cell specifically attracted was accomplished. Using HOZOT cell, We develop a nuclear medicine diagnostic method with the specificity for a cancer and are intended to aim at the application to the nuclear medicine cure for cancer more in this study. We succeeded in labelling HOZOT cell with indium-111, and I administered this intravenously to the mice with human breast cancer, and we imaged them with SPECT-CT device for animals, but unfortunately the accumulation of the HOZOT cell only was diffusely seen in the whole both lungs, and had little meaningful accumulation to the cancer organization. We could label HOZOT cell by nuclides except indium-111 and want to enable the imaging of a cancer with them in future.