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The role of autophagy in tumor-stromal cell interaction

The role of autophagy in tumor-stromal cell interaction
自噬在肿瘤-基质细胞相互作用中的作用
批准号:
24659615
负责人:
NAKATA Kohei
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31

项目摘要

项目成果

NAKATA Kohei的其他基金

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相关文献

中文摘要
翻译
我们从手术中获得的胰腺癌组织中建立了胰腺星状细胞。我们鉴定了每个胰腺星状细胞的自噬水平,发现每个细胞的自噬水平是不同的。我们还发现胰腺癌细胞株在与胰腺星状细胞共培养时侵袭力增加,并证实3MA可降低其侵袭力。
英文摘要
We established pancreatic stellate cells from pancreatic cancer tissue obtained during surgery. We identified the autophagy levels in each pancreatic stellate cells and found the levels were different in each cells. We also found the invasiveness of pancreatic cancer cell lines were increased with co-culture with pancreatic stellate cells and identified that its invasiveness was decreased with 3MA.
期刊论文(7)
专著(0)
科研奖励(0)
会议论文
DOI: --
发表时间:
期刊:
影响因子: --
作者: [K Nakata, et al, Nakata K et al]
通讯作者: Nakata K et al
Insulin-like growth factor II messenger RNA-binding protein-3 is a valuable diagnostic and prognostic marker of intraductal papillary mucinous neoplasm
胰岛素样生长因子 II 信使 RNA 结合蛋白 3 是导管内乳头状粘液性肿瘤有价值的诊断和预后标志物
DOI: --
发表时间: 2013
期刊: Hum Pathol
影响因子: 3.3
作者: [Morimatsu K, Aishima S, Yamamoto H, Hayashi A, Nakata K, Oda Y, Shindo K, Fujino M, Tanaka M, Oda Y]
通讯作者: Oda Y
DOI: 10.1245/s10434-014-3676-8
发表时间: 2014-12-01
期刊: ANNALS OF SURGICAL ONCOLOGY
影响因子: 3.7
作者: [Nakata, Kohei, Ohuchida, Kenoki, Tanaka, Masao]
通讯作者: Tanaka, Masao
MicroRNA-373 is down regulated in pancreatic cancer and inhibits cancer cell incasion
MicroRNA-373在胰腺癌中下调并抑制癌细胞侵袭
DOI: --
发表时间: 2014
期刊: Annals of Surgical Oncology
影响因子: 3.7
作者: [Nakata K, Ohuchida K, Mizumoto K, Aishima S, Nagai E, Oda Y and Tanaka M]
通讯作者: Oda Y and Tanaka M
Drug screening targeting pancreatic stellate cell activation
  • 批准号:
    18H02880
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.07万
  • 财政年份:
    2018
  • 负责人:
    NAKATA Kohei
  • 依托单位:
New drug discovery screening targeting autophagy
  • 批准号:
    16K15621
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.16万
  • 财政年份:
    2016
  • 负责人:
    NAKATA Kohei
  • 依托单位:
Elucidation of the role of microRNA as a cancer treatment-resistant mechanism by autophagy
  • 批准号:
    26670607
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.33万
  • 财政年份:
    2014
  • 负责人:
    NAKATA Kohei
  • 依托单位:
Elucidation of G0 phase maintenance mechanism by autophagy in cancer stem cells and development of artificial virus therapy method
  • 批准号:
    25713050
  • 项目类别:
    Grant-in-Aid for Young Scientists (A)
  • 资助金额:
    $16.14万
  • 财政年份:
    2013
  • 负责人:
    NAKATA Kohei
  • 依托单位:
海外基金