Pathogenesis of bleb formation in idiopathic pneumothorax

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Purpose: The Bleb, which can cause spontaneous pneumothorax development. We conducted a study in order to identify the presence of a specific pathogen in the formation of the Bleb. Method: From the lungs excised during spontaneous pneumothorax surgery, by extracting RNA and DNA, was subjected to gene search using a sensitive exhaustive search method pathogens.Result: Such as TTV, HHV-6, HHV-7, EBV, parvovirus B19 were detected from Bleb part. But these viruses are detected from the normal lung tissue, except parvovirus B19. Relevance of bleb formation and these pathogens unknown at this time. Conclusion: Identification of specific pathogens were unable to Bleb tissue that could be the pathogenesis of pneumothorax.