Strategy for regulation of cardiac functional defects due to the abnormality in molecular distribution caused by gene mutations

基因突变导致分子分布异常导致心脏功能缺陷的调控策略

• 批准号: 25670172
• 负责人: KIMURA Akinori
• 金额: $ 2.5万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2013
• 资助国家: 日本
• 起止时间: 2013-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-25670172/
• 关键词: 遺伝学; 遺伝子; ゲノム; 循環器・高血圧; 生体分子

项目成果

Novel calmodulin mutations associated with congenital arrhythmia susceptibility.

• DOI: 10.1161/circgenetics.113.000459
• 发表时间: 2014-08
• 期刊: Circulation. Cardiovascular genetics
• 作者: Makita N;Yagihara N;Crotti L;Johnson CN;Beckmann BM;Roh MS;Shigemizu D;Lichtner P;Ishikawa T;Aiba T;Homfray T;Behr ER;Klug D;Denjoy I;Mastantuono E;Theisen D;Tsunoda T;Satake W;Toda T;Nakagawa H;Tsuji Y;Tsuchiya T;Yamamoto H;Miyamoto Y;Endo N;Kimura A;Ozaki K;Motomura H;Suda K;Tanaka T;Schwartz PJ;Meitinger T;Kääb S;Guicheney P;Shimizu W;Bhuiyan ZA;Watanabe H;Chazin WJ;George AL Jr
• 通讯作者: George AL Jr

Impact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue

• DOI: 10.1007/s00395-013-0349-x
• 发表时间: 2013-05-01
• 期刊: BASIC RESEARCH IN CARDIOLOGY
• 影响因子: 9.5
• 作者: Crocini, Claudia;Arimura, Takuro;Carrier, Lucie
• 通讯作者: Carrier, Lucie