Proteomic screening for malignant melanoma antigen and development of antibody-based medicine for metastasis.

恶性黑色素瘤抗原的蛋白质组学筛查和基于抗体的转移药物的开发。

• 批准号: 25670508
• 负责人: NAKA TETSUJI
• 金额: $ 2.33万
• 依托单位: National Institutes of Biomedical Innovation, Health and Nutrition
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2013
• 资助国家: 日本
• 起止时间: 2013-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-25670508/
• 关键词: 癌; プロテオーム; タンパク質; 抗体; 悪性黒色腫; 抗体医薬; 蛋白質

项目成果

Annexin A4 induces platinum resistance in a chloride-and calcium-dependent manner.

• DOI: 10.18632/oncotarget.2306
• 发表时间: 2014-09-15
• 期刊: Oncotarget
• 作者: Morimoto A;Serada S;Enomoto T;Kim A;Matsuzaki S;Takahashi T;Ueda Y;Yoshino K;Fujita M;Fujimoto M;Kimura T;Naka T
• 通讯作者: Naka T

New findings of kinase switching in gastrointestinal stromal tumor under imatinib using phosphoproteomic analysis.

使用磷酸蛋白质组学分析在伊马替尼治疗下胃肠道间质瘤中激酶转换的新发现。

• DOI: 10.1002/ijc.28282
• 发表时间: 2013
• 期刊: Int J Cancer
• 影响因子: 6.4
• 作者: Takahashi T;Serada S;Ako M;Fujimoto M;Miyazaki Y;Nakatsuka R;Ikezoe T;Yokoyama A;Taguchi T;Shimada K;Kurokawa Y;Yamasaki M;Miyata H;Nakajima K;Takiguchi S;Mori M;Doki Y;Naka T;Nishida T.
• 通讯作者: Nishida T.

Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines.

• DOI: 10.18632/oncotarget.3557
• 发表时间: 2015-05-10
• 期刊: Oncotarget
• 作者: Takemoto N;Serada S;Fujimoto M;Honda H;Ohkawara T;Takahashi T;Nomura S;Inohara H;Naka T
• 通讯作者: Naka T

Calretinin mediates apoptosis in small cell lung cancer cells expressing tetraspanin CD9.

• DOI: 10.1016/j.fob.2013.04.005
• 发表时间: 2013
• 期刊: FEBS open bio
• 影响因子: 2.6
• 作者: He P;Kuhara H;Tachibana I;Jin Y;Takeda Y;Tetsumoto S;Minami T;Kohmo S;Hirata H;Takahashi R;Inoue K;Nagatomo I;Kida H;Kijima T;Naka T;Morii E;Kawase I;Kumanogoh A
• 通讯作者: Kumanogoh A

Proteomic identification of heterogeneous nuclear ribonucleoprotein K as a novel cold-associated autoantigen in patients with secondary Raynaud's phenomenon.

• DOI: 10.1093/rheumatology/keu325
• 发表时间: 2015-02
• 期刊: Rheumatology
• 影响因子: 5.5
• 作者: Lingli Yang;M. Fujimoto;H. Murota;S. Serada;M. Fujimoto;H. Honda;Kohji Yamada;Katsuya Suzuki;A. Nishikawa;Y. Hosono;Y. Yoneda;K. Takehara;Y. Imura;T. Mimori;T. Takeuchi;I. Katayama;T. Naka