The molecular role of ADAM12 in maintenance of skeletal muscle, myogenesis and adipogenesis

ADAM12 在维持骨骼肌、肌生成和脂肪生成中的分子作用

• 批准号: DP0663339
• 负责人: Prof Miranda Grounds
• 金额: $ 19.1万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-07-07 至 2009-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0663339
• 关键词: molecular; role; ADAM12; maintenance; skeletal

An understanding of the molecular control of skeletal muscle growth, maintenance and balance between muscle and fat production is of fundamental importance for a competitive meat industry, for the promotion of strong muscles in the ageing population and for disorders such as muscle diseases, diabetes and obesity. This project will enhance strong international collaborations and expand cutting-edge research within Australia with many potential economic benefits for the meat industry, biotechnology and health. The expertise developed by this pioneering research will ensure that Australia is well placed to harness new technologies and exploit future advances in this fast-moving field of muscle biology.

了解骨骼肌生长、维持以及肌肉和脂肪生产之间平衡的分子控制对于竞争性肉类工业、促进老龄人口中的强壮肌肉以及肌肉疾病、糖尿病和肥胖症等疾病具有根本重要性。该项目将加强强有力的国际合作，扩大澳大利亚的尖端研究，为肉类工业、生物技术和健康带来许多潜在的经济效益。 这项开创性研究所开发的专业知识将确保澳大利亚能够充分利用新技术，并利用肌肉生物学这一快速发展领域的未来进展。