What is the role of striatal dopamine in value-based decision-making?

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The aim of this project is to understand the role of dopamine in the brain circuits controlling goal-directed action. Its significance lies in our use of newly developed tools to measure dopamine release and cellular activity concurrently to assess the causal role of this interaction in choice and decision-making. The expected outcome of this project is to provide a comprehensive understanding of the role of dopamine release in striatal cellular activity and in the psychological processes mediating goal-directed decision-making. This outcome will have the benefit of filling a gap in our knowledge of the brain processes mediating decision-making, a fundamental capacity that contributes to our physical and psychological wellbeing (wellness).