Regulation of asymmetric cell division by the machinery maintaining genome stability

通过维持基因组稳定性的机制调节不对称细胞分裂

• 批准号: 15K14376
• 负责人: MIYAGAWA KIYOSHI
• 金额: $ 2.5万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15K14376/
• 关键词: 細胞周期; 不均等細胞分裂

项目成果

Rad54B serves as a scaffold in the DNA damage response that limits checkpoint strength

• DOI: 10.1038/ncomms6426
• 发表时间: 2014-11-01
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Yasuhara, Takaaki;Suzuki, Takahiko;Miyagawa, Kiyoshi
• 通讯作者: Miyagawa, Kiyoshi

The novel mechanism linking cell cycle regulation to cancer development

将细胞周期调控与癌症发展联系起来的新机制

• 发表时间: 2015
• 作者: Sugasawa;M.;Matsuzaki;R.;Kawafune;K.;Takahashi;T.;Kawachi;M.;Krienitz;L. and Nozaki;H.;伊澤大介;安川和孝・中村謙太郎・藤永公一郎・岩森光・加藤泰浩;安原 崇哲
• 通讯作者: 安原 崇哲

Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein.

• DOI: 10.1038/ncomms12808
• 发表时间: 2016-09-20
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Hashimoto, Takuma;Horikawa, Daiki D.;Saito, Yuki;Kuwahara, Hirokazu;Kozuka-Hata, Hiroko;Shin-, Tadasu, I;Minakuchi, Yohei;Ohishi, Kazuko;Motoyama, Ayuko;Aizu, Tomoyuki;Enomoto, Atsushi;Kondo, Koyuki;Tanaka, Sae;Hara, Yuichiro;Koshikawa, Shigeyuki;Sagara, Hiroshi;Miura, Toru;Yokobori, Shin-ichi;Miyagawa, Kiyoshi;Suzuki, Yutaka;Kubo, Takeo;Oyama, Masaaki;Kohara, Yuji;Fujiyama, Asao;Arakawa, Kazuharu;Katayama, Toshiaki;Toyoda, Atsushi;Kunieda, Takekazu
• 通讯作者: Kunieda, Takekazu

High RAD54B expression: an independent predictor of postoperative distant recurrence in colorectal cancer patients.

• DOI: 10.18632/oncotarget.4222
• 发表时间: 2015-08-28
• 期刊: Oncotarget
• 作者: Nagai Y;Yamamoto Y;Yasuhara T;Hata K;Nishikawa T;Tanaka T;Tanaka J;Kiyomatsu T;Kawai K;Nozawa H;Kazama S;Yamaguchi H;Ishihara S;Sunami E;Yamanaka T;Miyagawa K;Watanabe T
• 通讯作者: Watanabe T

The Rad54B-p53 axis limits the strength of DNA damage checkpoint

Rad54B-p53轴限制DNA损伤检查点的强度

• 发表时间: 2016
• 作者: Yoshii;D.; Jin;X.; Yatabe;T.; Hasegawa;J.; Yamaguchi;K.; Mizuno;N.;Takaaki Yasuhara
• 通讯作者: Takaaki Yasuhara