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Development of an efficient method for generation of genetically modified insulin secreting cells and its application for studies on insulin secretion

Development of an efficient method for generation of genetically modified insulin secreting cells and its application for studies on insulin secretion
一种高效的转基因胰岛素分泌细胞产生方法的开发及其在胰岛素分泌研究中的应用
批准号:
15K15351
负责人:
ISHIHARA Hisamitsu
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2017-03-31

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期刊论文(8)
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会议论文
Difficulty diagnosing acute pancreatitis possibly masked by severe hypertriglyceridemia in an obese patient with ketoacidosis-onset type 2 diabetes
患有酮症酸中毒的 2 型糖尿病肥胖患者难以诊断急性胰腺炎,可能被严重高甘油三酯血症所掩盖
DOI: --
发表时间: 2017
期刊: Int Med.
影响因子: --
作者: [Fujishiro M, Horita A, Nakagawara H, Mawatari T, Kishigami Y,Tominaga Y, Moriyama M, Ishihara H.]
通讯作者: Ishihara H.
Screening by RMCE-mediated generation of MIN6 cell transformants identifies novel genes important for insulin secretion
通过 RMCE 介导的 MIN6 细胞转化体筛选,鉴定出对胰岛素分泌重要的新基因
DOI: --
发表时间: 2015
期刊:
影响因子: --
作者: [Furukawa A, Tanaka A, Kosuda M, Otsuka Y, Yamaguchi S, Ishihara H.]
通讯作者: Ishihara H.
Establishment of efficient gene transfer system based on RMCE method in MIN6 cells, and new findings of novel genes involved in insulin secretion
基于RMCE方法在MIN6细胞中建立高效基因转移体系,并发现参与胰岛素分泌的新基因
DOI: --
发表时间: 2016
期刊:
影响因子: --
作者: [Yamaguchi S, Ishihara H]
通讯作者: Ishihara H
DOI: 10.1111/dom.12745
发表时间: 2016-12
期刊: Diabetes, obesity & metabolism
影响因子: --
作者: [Ishihara H, Yamaguchi S, Nakao I, Okitsu A, Asahina S]
通讯作者: Asahina S
7
    Metabolic features of hormone secreting cells in pancreatic islets and analyses of their dysfunction using pseudo-islets
    • 批准号:
      20K08918
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.75万
    • 财政年份:
      2020
    • 负责人:
      ISHIHARA Hisamitsu
    • 依托单位:
    Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysis
    • 批准号:
      17K09850
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2017
    • 负责人:
      ISHIHARA Hisamitsu
    • 依托单位:
    Analysis of glucagon seceretion mechanisms and its modulation by anti-diabetes drugs
    • 批准号:
      24591343
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.33万
    • 财政年份:
      2012
    • 负责人:
      ISHIHARA Hisamitsu
    • 依托单位:
    Molecular mechanisms of pancreaticβ-cell failure and insulin resistance due to impaired ER stress response
    • 批准号:
      21591147
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2009
    • 负责人:
      ISHIHARA Hisamitsu
    • 依托单位:
    海外基金