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Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysis

Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysis
通过大规模产生转基因胰岛素分泌细胞和组学分析来阐明胰岛素分泌机制
批准号:
17K09850
负责人:
ISHIHARA Hisamitsu
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2017
资助国家:
日本
项目状态:
已结题
起止时间:
2017-04-01 至 2020-03-31

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会议论文
DOI: 10.1016/j.celrep.2019.02.066
发表时间: 2019-03
期刊: Cell reports
影响因子: 8.8
作者: [Yusuke Nakatsu;Y. Matsunaga;Takeshi Yamamotoya;K. Ueda;Masa-Ki Inoue;Yu Mizuno;M. Nakanishi;T. Sano;Yosuke Yamawaki;A. Kushiyama;H. Sakoda;M. Fujishiro;A. Ryo;Hiraku Ono;T. Minamino;Shin-ichiro Takahashi;H. Ohno;M. Yoneda;Kei Takahashi;H. Ishihara;H. Katagiri;F. Nishimura;T. Kanematsu;Tetsuya Yamada;T. Asano]
通讯作者: Yusuke Nakatsu;Y. Matsunaga;Takeshi Yamamotoya;K. Ueda;Masa-Ki Inoue;Yu Mizuno;M. Nakanishi;T. Sano;Yosuke Yamawaki;A. Kushiyama;H. Sakoda;M. Fujishiro;A. Ryo;Hiraku Ono;T. Minamino;Shin-ichiro Takahashi;H. Ohno;M. Yoneda;Kei Takahashi;H. Ishihara;H. Katagiri;F. Nishimura;T. Kanematsu;Tetsuya Yamada;T. Asano
DOI: 10.3389/fneur.2019.00681
发表时间: 2019-07-04
期刊: FRONTIERS IN NEUROLOGY
影响因子: 3.4
作者: [Kohno, Genta, Ogawa, Katsuhiko, Fujishiro, Midori]
通讯作者: Fujishiro, Midori
Overexpression screening identifies mitochondrial carbonic anhydrase 5b as an important regulator of glucose-stimulated insulin secretion in beta-cells
过表达筛选发现线粒体碳酸酐酶 5b 是 β 细胞中葡萄糖刺激的胰岛素分泌的重要调节因子
DOI: --
发表时间: 2019
期刊:
影响因子: --
作者: [Kosuda M, Yamaguchi S, Nakasawa A, Yamana M, Koike M, NIshioka H, Ishihara H.]
通讯作者: Ishihara H.
DOI: 10.1038/s41598-017-13432-x
发表时间: 2017-10-12
期刊: Scientific reports
影响因子: 4.6
作者: [Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T]
通讯作者: Asano T
13
    Metabolic features of hormone secreting cells in pancreatic islets and analyses of their dysfunction using pseudo-islets
    • 批准号:
      20K08918
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.75万
    • 财政年份:
      2020
    • 负责人:
      ISHIHARA Hisamitsu
    • 依托单位:
    Development of an efficient method for generation of genetically modified insulin secreting cells and its application for studies on insulin secretion
    • 批准号:
      15K15351
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2015
    • 负责人:
      ISHIHARA Hisamitsu
    • 依托单位:
    Analysis of glucagon seceretion mechanisms and its modulation by anti-diabetes drugs
    • 批准号:
      24591343
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.33万
    • 财政年份:
      2012
    • 负责人:
      ISHIHARA Hisamitsu
    • 依托单位:
    Molecular mechanisms of pancreaticβ-cell failure and insulin resistance due to impaired ER stress response
    • 批准号:
      21591147
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2009
    • 负责人:
      ISHIHARA Hisamitsu
    • 依托单位:
    海外基金