Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysis
Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysis
批准号:
17K09850
负责人:
ISHIHARA Hisamitsu
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2017
资助国家:
日本
项目状态:
已结题
起止时间:
2017-04-01 至 2020-03-31
中文摘要
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英文摘要
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DOI:
10.1016/j.celrep.2019.02.066
发表时间:
2019-03
期刊:
Cell reports
影响因子:
8.8
作者:
[Yusuke Nakatsu;Y. Matsunaga;Takeshi Yamamotoya;K. Ueda;Masa-Ki Inoue;Yu Mizuno;M. Nakanishi;T. Sano;Yosuke Yamawaki;A. Kushiyama;H. Sakoda;M. Fujishiro;A. Ryo;Hiraku Ono;T. Minamino;Shin-ichiro Takahashi;H. Ohno;M. Yoneda;Kei Takahashi;H. Ishihara;H. Katagiri;F. Nishimura;T. Kanematsu;Tetsuya Yamada;T. Asano]
通讯作者:
Yusuke Nakatsu;Y. Matsunaga;Takeshi Yamamotoya;K. Ueda;Masa-Ki Inoue;Yu Mizuno;M. Nakanishi;T. Sano;Yosuke Yamawaki;A. Kushiyama;H. Sakoda;M. Fujishiro;A. Ryo;Hiraku Ono;T. Minamino;Shin-ichiro Takahashi;H. Ohno;M. Yoneda;Kei Takahashi;H. Ishihara;H. Katagiri;F. Nishimura;T. Kanematsu;Tetsuya Yamada;T. Asano
DOI:
10.3389/fneur.2019.00681
发表时间:
2019-07-04
期刊:
FRONTIERS IN NEUROLOGY
影响因子:
3.4
作者:
[Kohno, Genta, Ogawa, Katsuhiko, Fujishiro, Midori]
通讯作者:
Fujishiro, Midori
Overexpression screening identifies mitochondrial carbonic anhydrase 5b as an important regulator of glucose-stimulated insulin secretion in beta-cells
过表达筛选发现线粒体碳酸酐酶 5b 是 β 细胞中葡萄糖刺激的胰岛素分泌的重要调节因子
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[Kosuda M, Yamaguchi S, Nakasawa A, Yamana M, Koike M, NIshioka H, Ishihara H.]
通讯作者:
Ishihara H.
インスリン分泌におけるCITED4の機能解析
CITED4在胰岛素分泌中的功能分析
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[山口 賢]
通讯作者:
山口 賢
DOI:
10.1038/s41598-017-13432-x
发表时间:
2017-10-12
期刊:
Scientific reports
影响因子:
4.6
作者:
[Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T]
通讯作者:
Asano T
共 13 条
Metabolic features of hormone secreting cells in pancreatic islets and analyses of their dysfunction using pseudo-islets
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批准号:20K08918
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2020
-
负责人:ISHIHARA Hisamitsu
-
依托单位:
Development of an efficient method for generation of genetically modified insulin secreting cells and its application for studies on insulin secretion
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批准号:15K15351
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
-
财政年份:2015
-
负责人:ISHIHARA Hisamitsu
-
依托单位:
Analysis of glucagon seceretion mechanisms and its modulation by anti-diabetes drugs
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批准号:24591343
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2012
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负责人:ISHIHARA Hisamitsu
-
依托单位:
Molecular mechanisms of pancreaticβ-cell failure and insulin resistance due to impaired ER stress response
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批准号:21591147
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
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财政年份:2009
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负责人:ISHIHARA Hisamitsu
-
依托单位:
The molecular mechanisms of transcriptional and translational control of stress responses in pancreatic β cells
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批准号:19590300
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
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负责人:ISHIHARA Hisamitsu
-
依托单位:
Molecular Mechanisms for Pancreatic Islet Disfunction in Development of Diabetes Mellitus-a study using WFS1 knockout mice
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批准号:17590264
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2005
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负责人:ISHIHARA Hisamitsu
-
依托单位:
海外基金