Molecular physiological mechanism for discrimination of multipleneural signaling in neural circuit

为了确定辨别神经信息的分子和生理机制，我们使用了简单的局部神经回路来进行温度感觉和处理。我们利用了分子遗传学、行为分析和光学成像以及神经活动的操纵。W发现，通过谷氨酸神经传递识别多种温度信号的神经编码、感觉识别的分子机制和突触的定位机制涉及轴突的信息识别。

To identify molecular and physiological mechanisms for discrimination of neuralinformation, we used simple local neural circuit underlying temperature sensation andprocessing. We utilized molecular genetics, behavioral analysis and optical imaging andmanipulation of neural activity. W found that neural coding for discrimination of multipletemperatures signaling through glutamate neurotransmission, molecular mechanism fordiscrimination of sensations, and localization mechanisms of synapses involved ininformation discrimination in axon.