Comprehensive analysis of regulatory pathways controlling mammalian Golgi stress response
Comprehensive analysis of regulatory pathways controlling mammalian Golgi stress response
批准号:
23657136
负责人:
YOSHIDA Hiderou
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
The Golgi stress response is an autoregulatory mechanism controlling the capacity of the Golgi apparatus in accordance with cellular demands. We analyzed what kinds of molecular changes activate the Golgi stress response, and revealed that deficiency of glycosylation in the Golgi apparatus is responsible for activation of the Golgi stress response.
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Activation signal for the TFE3-GASE pathway of the mammalian Golgi stress response is originating from the damaged Golgi apparatus
哺乳动物高尔基体应激反应 TFE3-GASE 通路的激活信号源自受损的高尔基体
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Miki Yamamoto-Hino, Takako Shibano, Wakae Awano, Hideyuki Okano, Satoshi Goto, 岩崎秀雄, Mai Taniguchi]
通讯作者:
Mai Taniguchi
The activation mechanism of a transcription factor TFE3 regulating the mammalian Golgi stress response
转录因子TFE3调节哺乳动物高尔基体应激反应的激活机制
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[山本(日野)美紀, 粟野若枝, 芝野孝子, 岡野栄之, 後藤聡, Soichiro Tanakura]
通讯作者:
Soichiro Tanakura
Elsevier Comprehensive Biotechnology - Unfolded Protein Response
爱思唯尔综合生物技术 - 未折叠的蛋白质反应
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[K.Tanaka, et al., 庄村康人,樋口芳樹, 今本尚子, Mai Taniguchi and Hiderou Yoshida]
通讯作者:
Mai Taniguchi and Hiderou Yoshida
Transcription factor TFE3 is activated by dephosphorylation during mammalian Golgi stress response
哺乳动物高尔基体应激反应期间转录因子 TFE3 通过去磷酸化被激活
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Masayuki Murata, Fumi Kano, 吉田秀郎]
通讯作者:
吉田秀郎
Analysis of key transcription factors TFE3 and MLX regulating the mammalian Golgi stress response
调节哺乳动物高尔基体应激反应的关键转录因子TFE3和MLX分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Yukihiko Kubota, Yusuke Takabayashi, Kenji Tsuyama, Rika Maruyama, Asako Sugimoto, Shogo Sawaguchi]
通讯作者:
Shogo Sawaguchi
共 18 条
Picobiological analysis of the ER and Golgi stress responses
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批准号:25650070
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.66万
-
财政年份:2013
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负责人:YOSHIDA Hiderou
-
依托单位:
Regulatory network controlling mammalian Golgi stress response by bHLH-ZIP transcription factors
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批准号:22370069
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2010
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负责人:YOSHIDA Hiderou
-
依托单位:
Transcriptional regulatory mechanism of Golgi stress response
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批准号:19370086
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
-
财政年份:2007
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负责人:YOSHIDA Hiderou
-
依托单位:
Regulation of ER stress response by cytoplasmic mRNA splicing
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批准号:17370061
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.41万
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财政年份:2005
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负责人:YOSHIDA Hiderou
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依托单位:
海外基金