Regulation of juvenile hormone biosynthesis by ecdysis triggering hormone

蜕皮触发激素对保幼激素生物合成的调节

• 批准号: 23658044
• 负责人: HIRUMA Kiyoshi
• 金额: $ 2.5万
• 依托单位: Hirosaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23658044/
• 关键词: 昆虫生理学; 脱皮行動誘導ホルモン; 幼若ホルモン; 変態; 行動; 脱皮

Ecdysis triggering hormone (ETH) produced by Inka cells is a peptide hormone that induces insect ecdysis. We found that (1) ETH mRNA expression occurred in the corpora allata (CA) shortly before the last larval ecdysis, (2) EHT stimulated juvenile hormone (JH) biosynthesis by CA, and this stimulative action was observed primarily 6 hr before the last larval ecdysis, which was corresponded with the increase in JH synthesis during the molt. These results indicate that the increase in the JH titer during the last larval molt is due to the ETH action. Thus, a single hormone mediates two different phenomena, behavior and growth; a hormone that is responsible for behavior regulates JH synthesis, a key hormone involved in growth and metamorphosis.

由印加细胞产生的蜕皮触发激素(ETH)是一种诱导昆虫蜕皮的多肽激素。结果表明：(1)ETH mRNA在末龄幼虫蜕皮前不久在唇体(CA)中表达，(2)EHT可通过CA刺激保幼激素(JH)的生物合成，这种刺激作用主要在末龄幼虫蜕皮前6h观察到，这与蜕皮过程中JH合成的增加相一致。这些结果表明，在最后一次幼虫蜕皮期间，JH滴度的增加是由于ETH的作用。因此，一种激素调节两种不同的现象，行为和生长；负责行为的激素调节JH合成，JH合成是参与生长和变态的关键激素。

项目成果

脱皮行動誘導ホルモン(ETH)による幼若ホルモン生合成の促進

蜕皮行为诱导激素（ETH）促进保幼激素生物合成

• 发表时间: 2012
• 作者: Misako Himeno;et al;三好洋,ArtemV.Domashevskiy,中島秀喜,DixieJ.Goss;金児雄・比留間潔
• 通讯作者: 金児雄・比留間潔