Dynamics of nuclear architecture involving in reprogramming of mouse somatic nuclear transfer embryos
Dynamics of nuclear architecture involving in reprogramming of mouse somatic nuclear transfer embryos
批准号:
23658228
负责人:
MITANI Tasuku
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
This study examined the dynamics of chromatin composition in the early development of somatic cell nuclear transfer (SCNT) embryos. The results are summarized as follows: (1) histone composition of the SCNT embryos differs from that of the fertilized ones, (2) a certain histone variant is removed from chromatin by histone deacetylase (HDAC) inhibitors, and (3) responsiveness of histone modification and disposition depends on HDAC inhibitors and/or the types of cells.
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トゲネズミ研究の最近3~琉球諸島哺乳類保全の次世代を担う者達~.
最近对刺鼠的研究 - 那些负责下一代琉球群岛哺乳动物保护的人。
DOI:
--
发表时间:
2013
期刊:
哺乳類科学
影响因子:
--
作者:
[城ヶ原貴通, 山田文雄, 越本知大, 黒岩麻里, 木戸文香、中家雅隆, 望月春佳, 村田知慧, 三谷匡.]
通讯作者:
三谷匡.
Nuclear dynamics in chromosome territories and gene loci under in vitro differentiation of mouse embryonic stem cells.
小鼠胚胎干细胞体外分化下染色体区域和基因位点的核动力学。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kawaguchi S, Hirano D, Hosoi Y, Anzai M, Tanabe H, Mitani T.]
通讯作者:
Mitani T.
GSE is a maternal factor for DNA demethylation in early embryos
GSE是早期胚胎DNA去甲基化的母体因素
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Hatanaka Y, Shimizu N, Morita K, Nishikawa S, Nishihara T, Kato R, Takemoto A, Higuchi C, Amano T, Kishigami S, Anzai M, Kato H, Mitani T, Hosoi Y, Matsumoto K]
通讯作者:
Matsumoto K
Dnmt1p ノックダウンマウスの解析
Dnmt1p 敲除小鼠分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[加藤博己, 明野美穂, 北村亮, 山口広生, 沼田雄基, 木島隆之, 安齋政幸, 三谷匡, 松本和也, 佐伯和弘, 細井美彦, 入谷明]
通讯作者:
入谷明
Looping out of gene loci of hepatocyte specific gene Tdo2 in chromosome territories under the in vitro differentiation of mouse embryonic stem cells
小鼠胚胎干细胞体外分化过程中染色体区肝细胞特异性基因Tdo2基因位点的环出
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kawaguchi S, Emoto T, Hosoi Y, Tanabe H, Mitani T]
通讯作者:
Mitani T
共 31 条
Molecular mechanisms of ABC transporter, Bcrp1, in the oxidative stress response in mouse embryonic stem cells
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批准号:26450460
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2014
-
负责人:MITANI Tasuku
-
依托单位:
Molecular mechanisms of ABC transporter, Bcrp1, on the regulation of differentiation in mouse embryonic stem cells
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批准号:20580316
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2008
-
负责人:MITANI Tasuku
-
依托单位:
Development of genetically engineered animals by use of non-B DNA structure for highly and stably expression of transgene
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批准号:20200032
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项目类别:Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
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资助金额:$21.47万
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财政年份:2008
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负责人:MITANI Tasuku
-
依托单位:
Role of ABC transporter Bcrp 1 in maintenance of pluripotency in mouse embryonic stem cells
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批准号:18580283
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2006
-
负责人:MITANI Tasuku
-
依托单位:
Identification and separation of pluripotential tissue stem cells and its application for producing somatic cell nuclear transferred cloned mouse
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批准号:15580251
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:2003
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负责人:MITANI Tasuku
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依托单位:
海外基金