Analysis of idiosyncratic drug toxicity using mitochondria isolated from an animal model of metabolic syndrome
Analysis of idiosyncratic drug toxicity using mitochondria isolated from an animal model of metabolic syndrome
批准号:
26670084
负责人:
HORIE Toshiharu
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-04-01 至 2016-03-31
中文摘要
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英文摘要
期刊论文(10)
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生活習慣病モデル動物を用いたミトコンドリア薬物感受性の解析
使用生活方式相关疾病模型动物分析线粒体药物敏感性
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[濱田 和真, 中埜 貴文, 堀江 利治]
通讯作者:
堀江 利治
2型糖尿病時の肝臓ミトコンドリアにおける薬物障害性の解析
2型糖尿病时药物对肝线粒体的损伤分析
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[濱田和真, 桜田啓広, 齋藤希衣, 中埜貴文, 堀江利治]
通讯作者:
堀江利治
C型肝炎ウイルスが惹起する細胞内ポルフィリン代謝異常についての検討
丙型肝炎病毒引起的细胞内卟啉代谢异常的研究
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[中埜貴文, 濱田和真, 森屋恭爾, 小池和彦, 堀江利治]
通讯作者:
堀江利治
DOI:
10.1016/j.tiv.2015.06.004
发表时间:
2015-10
期刊:
Toxicology in vitro : an international journal published in association with BIBRA
影响因子:
--
作者:
[Takeshi Susukida;Shuichi Sekine;Eiichiro Ogimura;Shigeki Aoki;K. Oizumi;T. Horie;Kousei Ito]
通讯作者:
Takeshi Susukida;Shuichi Sekine;Eiichiro Ogimura;Shigeki Aoki;K. Oizumi;T. Horie;Kousei Ito
Metabolic activation of hepatotoxic drug (benzbromarone) induced mitochondrial membrane permeability transition.
肝毒性药物(苯溴马隆)的代谢激活诱导线粒体膜通透性转变。
DOI:
10.1016/j.taap.2015.06.018
发表时间:
2015
期刊:
Toxicol Appl Pharmacol
影响因子:
--
作者:
[Shirakawa M, Sekine S, Tanaka A, Horie T, Ito K.]
通讯作者:
Ito K.
共 9 条
Quantitative analysis of drugs induced BSEP inhibition and cholestatic hepatotoxicity
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批准号:23659073
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:HORIE Toshiharu
-
依托单位:
Molecular analysis of localization of biliary transporters in chronic hepatitis
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批准号:21249003
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$29.62万
-
财政年份:2009
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负责人:HORIE Toshiharu
-
依托单位:
Intrahepatic imaging and molecular analysis of MRP2 localization regulated by the intracellular redox status
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批准号:18390012
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.97万
-
财政年份:2006
-
负责人:HORIE Toshiharu
-
依托单位:
MRP2 mediated defense against oxidative stress in liver
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批准号:16390014
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.59万
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财政年份:2004
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负责人:HORIE Toshiharu
-
依托单位:
Evaluation of drug-induced hepatotoxicity by chemiluminescence and the role of MRP2 in the hepatotoxicity
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批准号:13470476
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.3万
-
财政年份:2001
-
负责人:HORIE Toshiharu
-
依托单位:
The drug-induced hepatotoxicity
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批准号:09470491
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.95万
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财政年份:1997
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负责人:HORIE Toshiharu
-
依托单位:
Pharmacokinetics and Hepatotoxicity due to the oxidative stress
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批准号:06672155
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.15万
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财政年份:1994
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负责人:HORIE Toshiharu
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依托单位:
A Study on Protective Effect of Vitamin A against Antitumour Drug-Induced Damage to Small Intestine
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批准号:03671067
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1991
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负责人:HORIE Toshiharu
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依托单位:
Quantitative Evaluation and Prediction of Drug-Toxicity Due to Lipid Peroxidation
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批准号:63571061
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1988
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负责人:HORIE Toshiharu
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依托单位:
海外基金