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Development of stone-disintegrater for upper urinary tract calculi using focused underwater shock waves

Development of stone-disintegrater for upper urinary tract calculi using focused underwater shock waves
开发利用水下聚焦冲击波治疗上尿路结石的碎石机
批准号:
59870052
负责人:
KUWAHARA Masa-aki
金额:
$4.93万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Developmental Scientific Research
财政年份:
1984
资助国家:
日本
项目状态:
已结题
起止时间:
1984 至 1985

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中文摘要
翻译
本文研究了高压电火花或微爆炸产生的水下冲击波的聚焦作用,以达到体外碎石的目的,并取得了以下结果.爆炸材料叠氮化铅丸产生的冲击波可以以与高压火花产生的冲击波相同的方式聚焦。聚焦冲击波对人体结石或模型结石的粉碎无困难.将提取的人结石或模型结石植入活体狗肾中,并将结石对准椭球反射镜的焦点区域。冲击波由10 mg叠氮化铅小球在反射器内微爆炸产生。结石在肾脏内崩解,未损伤包括肾脏在内的腹部器官,除检查外,还通过显微镜检查证实。在动物实验之后,使用原型粉碎机进行临床应用。1985年4月至1986年2月,我们应用体外微爆碎石术(EML)治疗结石100例。碎石成功率达95%以上,效果满意。在这方面,还需要进一步调查。
英文摘要
We studied on the focusing of underwater shock wave, generated by high voltage sparks, or microexplosions, for the purpose of extra corporeal renal stone disintegration, and obtained following results.1. The shock wave generated by explosive material, lead azide pellet, could be focused in the same manner as the shock wave generated by high voltage sparks. The focused shock wave disintegrated extracted human calculi, or model calculi without difficulty.2. Either extracted human calculus or model calculus was implanted in a living dog kidney, and the calculus was targeted at the focus area of an ellipsoidal reflector. The shock waves were generated by microexplosions of lead azide pellet of 10mg, inside the reflector. The calculus was disintegrated in the kidney without damaging abdominal organs, including the kidney, which was confirmed by microscopic examination, in addition to the inspection.3. Following to the animal experimets, the clinical applications were performed using a proto-type of disintegrator. From April, 1985 to February, 1986, we applied the method, extracorporeal microexplosive lithotripsy (EML), to 100 stone-patients. The results were satisfactory, the success rate of stone disintegration was more than 95 %.Improvements of the system are necessary to its wide and easy use. In this regard, further investigations are also required.
期刊论文(10)
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科研奖励(0)
会议论文
日本泌尿器科学会雑誌. 76. (1985)
日本泌尿外科协会杂志。76。(1985)
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医用電子と生体工学. 22. (1984)
医疗电子和生物工程22。(1984)
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日本超音波医学会講演論文集. 45. (1984)
日本超声医学会会刊 45。(1984 年)
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共 10 条
    Development of the system for extracorporeal stone disintegration using microexplosion;Disintegration of renal and gall stone.
    • 批准号:
      61870061
    • 项目类别:
      Grant-in-Aid for Developmental Scientific Research
    • 资助金额:
      $16.64万
    • 财政年份:
      1986
    • 负责人:
      KUWAHARA Masa-aki
    • 依托单位:
    海外基金