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Development of compouterized systems for processing and analysing the low frequencey biological time series.

开发用于处理和分析低频生物时间序列的计算机化系统。

基本信息

批准号：
61840024
负责人：
CHIBA Yoshihiko
金额：
$ 5.25万
依托单位：
Yamaguchi University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Developmental Scientific Research
财政年份：
1986
资助国家：
日本
起止时间：
1986 至 1988
项目状态：
已结题

项目摘要

Animal behaviors are rhythmic with periods ranging from hours to years. Recently, not only in the basic biology but in the applied field such as medicine. pharmacology, and agriculture, there is an increased number of researchers on the mechanism of these rhythmicities.For example, in the pharmaceutical industry, they started checking the effect of drug on the periodic behavior. In psychiatry, attention is now paid to the periodic behavior much more than ever, since some psychiatric or emotional disorders were found to be accompanied with abnormal rhythmicity in behaviors.In the study of biological rhythms, a huge amount of time series data has to be analyzed. This has been embarrassing the researcher. To relieve them from such trouble, it has been required to develop a inexpensive system that records, processes, and analyzes the biological time series and is easy to handle.In order to meet such a requirement, we organized the study team to develop the compact computerized system. By holding frequent meetings, we investigated problems which the researcher has been encountering and, eventually, developed the two alternative sets of system as follows, so that the desire of researchers may be satisfied as much as possible.(1) A system having 128 channels, which may be convenient in measuring many animals simultanously in a large laboratory.(2) A system with a restricted number (6) of channels, easier to handle for a small laboratory and for a beginner such as a high school student.Utility of these systems has already been demonstrated. Now we are ready to manufacture them in cooperation with two industrial companies, Japan System and Iwasaki Tsushinki.

动物的行为是有节奏的，周期从几小时到几年不等。最近，不仅在基础生物学领域，而且在医学等应用领域。药理学和农业方面，越来越多的研究人员研究这些节律性的机制。例如，在制药行业，他们开始检查药物对周期性行为的影响。在精神病学中，现在比以往任何时候都更加关注周期性行为，因为一些精神或情绪障碍被发现伴随着异常的行为节律。在生物节律的研究中，需要分析大量的时间序列数据。这让研究人员很尴尬。为了减轻他们的麻烦，需要开发一种廉价的系统来记录、处理和分析生物时间序列，并且易于操作。为了满足这样的要求，我们组织了研究小组开发了紧凑的计算机化系统。通过经常召开会议，我们调查了研究人员遇到的问题，最终开发了如下两套替代系统，以便尽可能满足研究人员的愿望。（1）具有128个通道的系统，可以方便地在大型实验室中同时测量许多动物。（2）通道数量有限（6）的系统，对于小型实验室和高中等初学者来说更容易操作学生。这些系统的实用性已经得到证明。现在我们准备与两家工业公司Japan System 和Iwasaki Tsushinki 合作生产它们。