Development of Non-Invasive Deep Heating Equipment for Local Hyperthermia.
Development of Non-Invasive Deep Heating Equipment for Local Hyperthermia.
批准号:
61870044
负责人:
KATO Hirokazu
金额:
$16.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Developmental Scientific Research
财政年份:
1986
资助国家:
日本
项目状态:
已结题
起止时间:
1986 至 1988
中文摘要
将电磁能量转化为身体的深层部分。需要一个较低频率的射频。应用程序驱动于低频率包括1)电容型应用程序, 2)诱导型应用程序, 3) Ridge waveguide型应用程序,4) horn型应用程序。他们有自己的问题,所以我们设计了一种有意义的药物类型申请人,国际航空运输协会,目的是解决这些问题。应用程序的6张铜条的尺寸在0.3毫米厚。申请人是一个3/4转弯的正方形线圈,它像俄罗斯字母弯曲的形状。PI"。作为一种普通的表面服务。使用IATA、Inductron"、用于clinical use的We?ed heating equipment with IATA、Inductron"、用于clinical use。电感器在13.56兆赫时驱动,最大功率为10千瓦。床、植物和感应器的应用者都可以在不同的方向上移动,因此,孔径可以面对患者身体的任何部分。八名患者在辐射治疗后被治疗过两次,一周后,一名患者在一周内被应用了五次,另一名患者被单独治疗过超热。四名19名患者有一个金属皮肤的部分,位于皮肤表面的0.5厘米。19名患者的肿瘤位于皮肤深处1至5厘米处。热量被应用到没有与申请人接触的身体上。肿瘤的最高温度为48.3 ° C,而肿瘤在42 ° C以上10 - 50分钟内升温。总体答复率为13/19。但没有没有辐射治疗和没有超热治疗的患者的反应率不到4次,已经有12/14。我们计划在以后处理深层座位的肿瘤。
英文摘要
To deliver electromagnetic energy to a deep portion of the body. RF at a lower frequency is needed. Appricators driven at lower frequency include 1) capacitive type applocator, 2)inductive applicator, 3) ridge waveguide type applicator filled with water, and 4) horn type applicator. They have their own problems so that we designed an inductive aperture-type applicator, IATA, for the purpose of resolving their problems. The applicator consists of 6 sheets of copper strips 0.3 mm in thickness. The applicator is a 3/4-turn square coil made of the strips which are bent like the shape of the Russian letter. "PI". One of the surfaces serves as an aperture. We developed heating equipment with IATA, "Inductron", for clinical use. The Inductron is driven at 13.56 MHz with a maximum power of 10 KW. The bed, the gantry, and the applicator of the Inductron are movable in various directions, so that the aperture can face any portion of the patients' body. Eighteen patients were treated with hyperthermia twice a week just after radiation therapy which was applied 5 times a week, and one patients was treated with hyperthermia alone. Four of 19 patients had metastatic skin lesions located within 0.5 cm of the skin surface. Fifteen of 19 patients had tumors located 1 to 5 cm in depth from the skin. Heat was applied to the body without contact to the applicator. The highest temperature in the tumor was 48.3゜C and the tumors were heated above 42゜C for 10 to 50 minutes. The overall respose rate is 13/19. But the response rate without the patient who had hyperthermia treatment without radiation therapy and had hyperthermia treatment less than 4 times was 12/14. We plan to treat deep seated tumors hereafter.
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Kato,H.;Ishida,T.: Japn.J.Radiological Tech.6. 187-189 (1987)
加藤,H.;石田,T.:Japn.J.Radiological Tech.6。
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Kato,H.;Ishida,T.: Phys.Med.Biol.32. 221-226 (1987)
加藤,H.;石田,T.:Phys.Med.Biol.32。
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Kato,H.;and Ishida,T.: Proceedings of the 5th International Symposium on Hyperthrermic Oncology.
Kato,H.;和 Ishida,T.:第五届国际高热肿瘤学研讨会论文集。
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Uchida,N.;Kato,H.;Furukawa,M.;Kasai,T.;Fujita,Y.;Ishida,T.: Proceedings of the 5th International Symposium on Hyperthermic Oncology.
Uchida,N.;Kato,H.;Furukawa,M.;Kasai,T.;Fujita,Y.;Ishida,T.:第五届国际热肿瘤学研讨会论文集。
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Kato, H.: "Deep heating technique by RF capacitive type heating" Proceedings of the lst Japan-China Bilateral Symposium on Radiosensitization. 32-39 (1985)
Kato, H.:“射频电容式加热的深层加热技术”第一届日中放射增敏双边研讨会论文集。
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共 82 条
Development of a reliable and accurate augmented reality technology for high-risk task support
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Development of MRI system for dentistry
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依托单位:
Development of a phantom compatible for MRI and hyperthermia equivalent to relaxation times and dielectric properties of the human tissues
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资助金额:$2.3万
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