Rapid adaptive change through high recombination rates in eusocial insects

真社会性昆虫通过高重组率实现快速适应性变化

• 批准号: 403813881
• 负责人: Privatdozent Dr. Jan Oettler
• 金额: --
• 依托单位: Arbeitsgruppe Evolution, Verhalten und Genetik
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2018
• 资助国家: 德国
• 起止时间: 2017-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/403813881?language=en
• 关键词: Rapid; adaptive; change; through; recombination

Structural variants (deletions, insertions, duplications, inversions, translocations) are the largest source of inter-individual genetic variation. They arise frequently, often in a single mutagenic event, for example during non-allelic homologous recombination. Social Hymenoptera have the highest recombination rates of all so far studied animals, suggesting that structural variation might be particularly abundant in populations of these species. Due to small effective population sizes of social insects, structural variants can become fixed rapidly. Previous work on the invasive ant Cardiocondyla obscurior has shown a variety of structural variants between isolated populations (Schrader et al. 2014), likely contributing to the emergence of locally adapted phenotypes such as pesticide resistance and changes in aggressive behavior related to nestmate recognition. By studying populations of C. obscurior in the field and laboratory combining bio assays, linkage mapping, population genomics, and molecular tools, we will explore the role of very high recombination rates and structural genetic variation in rapid adaption of invasive social Hymenoptera.

结构变异（缺失、插入、重复、倒位、易位）是个体间遗传变异的最大来源。它们经常出现，通常在单一诱变事件中，例如在非等位基因同源重组期间。社会Hyquitera有最高的重组率，所有迄今为止研究的动物，这表明，结构变异可能是特别丰富的人口，这些物种。由于群居昆虫的有效种群规模很小，结构变异可以迅速固定。先前对入侵蚂蚁隐翅虫的研究表明，隔离种群之间存在多种结构变异（Schrader et al. 2014），这可能有助于出现局部适应表型，如杀虫剂抗性和与巢友识别相关的攻击行为变化。通过对C.结合生物测定、连锁图谱、群体基因组学和分子工具，我们将探索非常高的重组率和结构遗传变异在入侵性社会性水虻快速适应中的作用。