Selective synthesis of high value-added products with chiral carbon atoms containing from sugars over heterogeneous catalysts

非均相催化剂上糖类选择性合成含手性碳原子的高附加值产品

• 批准号: 21K14458
• 负责人: 曹 霽
• 金额: $ 3万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2021
• 资助国家: 日本
• 起止时间: 2021-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21K14458/
• 关键词: deoxydehydration; heterogeneous catalyst; sugar conversion; biomass conversion; 脱酸素脱水反応; 固体触媒; 糖類変換; 水素; バイオマス; Heterogenous catalyst; Sugar conversion; Deoxydehydration; Chiral polyols; Deoxy sugars

Erythritol is a typical C4 sugar alcohol, and it can be an important building block in biomass refinery because of a possibility of its production by fermentation of glycerol, as well as glucose. Recently, erythritol was selected as the substrate for the deoxydehydration and hydrogenation (DODH + HG) over CeO2 supported Re catalsyt, and the kinetic modelling had been conducted. During the reaction, DODH + HG of primary-secondary vicinal OH groups in erythritol gives 1,2-butanediol while the consecutive DODH + HG of 1,2-butanediol results in n-butane. Contrary to it DODH+HG of 1,4-butanediol, formed as a product DODH + HG of the secondary-secondary vicinal OH groups in erythritol, does not proceed further. Moreover, it is envisaged that in the modelling of DODH + HG of erythritol will be connected to the prediction and the interpretation of the product distribution in DODH+HG of more complex sugars, i.e. xylitol and sorbitol.

赤藓糖醇是一种典型的C4糖醇，由于其可以通过发酵甘油以及葡萄糖来生产，因此它可以是生物质精炼中的重要构件。最近，在CeO_2负载的Re催化剂上，选择铼作为脱氧脱水和氢化（DODH + HG）的底物，并进行了动力学模拟。在反应过程中，顺丁烯二醇中的伯-仲邻位OH的DODH + HG生成1，2-丁二醇，而1，2-丁二醇中的连续DODH + HG生成正丁烷。与此相反，1，4-丁二醇的DODH+HG，作为仲-仲邻位OH基团的产物DODH + HG形成于丁二醇中，不进一步进行。此外，设想在对D 0 DH + HG的建模中，将与更复杂的糖（即木糖醇和山梨糖醇）在D 0 DH +HG中的产物分布的预测和解释相关联。

项目成果

The 9th Tokyo Conference on Advanced Catalytic Science and Technology

第9届东京先进催化科学技术会议

• 发表时间: 2022

Mechanism of Deoxydehydration of Methyl Glycosides with cis-vicinal OH groups over ReOx-Pd/CeO2 Catalyst

ReOx-Pd/CeO2 催化剂上顺邻羟基甲基糖苷脱氧脱水机理

• 发表时间: 2022
• 作者: Ji Cao;Masazumi Tamura;Akira Nakayama;Yoshinao Nakagawa;Keiichi Tomishige
• 通讯作者: Keiichi Tomishige

Hydrodeoxygenation of potential platform chemicals derived from biomass to fuels and chemicals

将生物质衍生的潜在平台化学品加氢脱氧为燃料和化学品

• DOI: 10.1039/d2gc01289h
• 发表时间: 2022
• 期刊: Green Chemistry
• 影响因子: 9.8
• 作者: Tomishige Keiichi;Yabushita Mizuho;Cao Ji;Nakagawa Yoshinao
• 通讯作者: Nakagawa Yoshinao

Deoxydehydration and hydrogenation of methyl glycosides to dideoxy sugars over ReOx-Pd/CeO2 catalys

ReOx-Pd/CeO2 催化剂上甲基糖苷脱氧脱水和氢化生成双脱氧糖

• 发表时间: 2022
• 作者: Ji Cao;Masazumi Tamura;Akira Nakayama;Yoshinao Nakagawa;Keiichi Tomishige
• 通讯作者: Keiichi Tomishige

Catalytic transformation of methyl glycosides with cis-vicinal OH groups to dideoxy and unsaturated sugars by deoxydehydration with H2

具有顺邻羟基的甲基糖苷通过氢气脱氧脱水催化转化为双脱氧和不饱和糖

• 发表时间: 2021
• 作者: Ji Cao,Masazumi Tamura;Yoshinao Nakagawa;Keiichi Tomishige
• 通讯作者: Keiichi Tomishige