Applications of muon in cancer research

μ介子在癌症研究中的应用

• 批准号: 21K15583
• 负责人: PANT Amba・Datt
• 金额: $ 2.91万
• 依托单位: High Energy Accelerator Research Organization
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2021
• 资助国家: 日本
• 起止时间: 2021-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21K15583/
• 关键词: Hypoxia; muonium; tumor; cancer; muon and muonium; muon technique

Main goal of this research is to detect the molecular oxygen in biosamples using muon method to apply the muon method in cancer research. The long-term goal is to apply sensitive probe of muon for early diagnosis and management of cancer. Since the water and molecular oxygen are existed in the biosamples, I have planned to perform systematic study starting from water, oxygen dependent in water, buffer and biosamples. So far, I have studied the muon and muonium behavior in water and ice and explained the data satisfactorily using proposed new model. As a next step, the detection of oxygen in biosamples (hemoglobin, blood plasma) and inhomogeneous system of hemoglobin and blood plasma will be performed within the project period.

本研究的主要目的是利用μ子方法检测生物样品中的分子氧，将μ子方法应用于癌症研究。长期目标是将μ子敏感探针应用于癌症的早期诊断和治疗。由于水和分子氧存在于生物样品中，我计划从水、水中的氧依赖性、缓冲液和生物样品开始进行系统研究。到目前为止，我已经研究了水和冰中的μ子和μ 鎓的行为，并使用所提出的新模型满意地解释了数据。下一步，将在项目期间进行生物样本（血红蛋白、血浆）中的氧检测以及血红蛋白和血浆的非均质系统。

项目成果

Kathmandu University(ネパール)

加德满都大学（尼泊尔）

Overview of muSR Study in Water and Ice

水和冰中 muSR 研究概述

• DOI: 10.3126/jnphyssoc.v7i3.42186
• 发表时间: 2021
• 期刊: Journal of Nepal Physical Society
• 作者: Amba Datt Pant;Amba Datt Pant
• 通讯作者: Amba Datt Pant

Muonium and Water in Histidine Amino Acid

组氨酸氨基酸中的锷和水

• DOI: 10.3126/jnphyssoc.v7i2.38624
• 发表时间: 2021
• 期刊: Journal of Nepal Physical Society
• 作者: Amba Datt Pant;Amba Datt Pant;Amba Datt Pant
• 通讯作者: Amba Datt Pant

Optimization of momentum of muon beam and thickness of cell-window for muon experiment in bio-sample: a simulation study

生物样品μ子实验中μ子束动量和细胞窗口厚度的优化：模拟研究

• DOI: 10.3126/bibechana.v19i1-2.46413
• 发表时间: 2022
• 期刊: BIBECHANA
• 作者: Amba Datt Pant

Applications of quantum beam of muon in biology

μ子量子束在生物学中的应用

• 发表时间: 2023
• 作者: Amba Datt Pant;Amba Datt Pant;Amba Datt Pant;Amba Datt Pant;Amba Datt Pant
• 通讯作者: Amba Datt Pant