Modulating symptoms of early psychosis in Parkinson's disease using non-invasive brain stimulation

完成TMS和帕金森病非运动症状相关文献综述。完成IRB要求和jRCT注册（特定临床试验，Osaka University IRB编号S21002，jRCT编号：jRCTs 052210061）可行性检查实验数量= 5;符合合格性标准的患者总数= 8（截至2022年10月）;完成测试（真实的和假TMS刺激）= 3例患者。 已完成一次IRB审查委员会会议，以确定CRF（病例报告表）的进度、质量控制和文件检查。在两次国内研讨会上讨论了与项目有关的最新情况。该项目的一部分也在AMED-星际倡议计划2021-2022中向博士后研究人员和终身教职人员展示。今年晚些时候（2023年），计划举办一次国际研讨会（与印度）。评估方案涉及眼动跟踪、EEG，以及在一定程度上，测试期间的运动捕捉（头部运动），这些都是通过单独的仪器/设备测量的。这些设备的同步是在外部完成的，目前正在审查，以制定基于单一软件的方法。

Completion of review of literature related to TMS and Parkinson’s disease non-motor symptoms. Completion of IRB requirements and jRCT registration (Specific clinical trial, Osaka University IRB number S21002, jRCT no: jRCTs052210061)Number of feasibility check experiments = 5; Total number of patients satisfying eligibility criteria = 8 (as of Oct 2022); Testing completed (both Real and Sham TMS stimulation) = 3 patients. One IRB review board meeting has been completed to ascertain the progress, quality control and documentation check of CRF (Case report forms). Project related updates were discussed in 2 domestic seminars. A part of the project was also showcased for post-doctoral researchers and tenure-tracked staff in AMED-Interstellar Initiative program 2021-2022. Later this year (2023), One international seminar (with India) is planned. The evaluation protocol involves eye-tracking, EEG, and to some extent, motion capture (head motion) during testing, which is measured by separate instruments / equipment. Synchronization of these equipment is done externally and is currently being reviewed to make a single software based approach.