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Role of platelets in tissue remodelling and functional recovery after experimental cerebral ischaemia (B04+)

Role of platelets in tissue remodelling and functional recovery after experimental cerebral ischaemia (B04+)
血小板在实验性脑缺血后组织重塑和功能恢复中的作用(B04)
批准号:
406447995
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
德国
项目类别:
CRC/Transregios
财政年份:
2018
资助国家:
德国
项目状态:
已结题
起止时间:
2017-12-31 至 2021-12-31

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英文摘要
In B04, we will assess whether platelets play a pathophysiological role during post-stroke recovery and late-stage tissue remodelling. The main focus will be on platelet-mediated thrombo-inflammation as well as potential extravascular effects of platelets, e.g. induction of apoptosis. Translationally meaningful mouse models, novel pharmacological inhibitors, and advanced imaging techniques will be used to investigate our research questions.
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